Primary antiphospholipid syndrome (APS) is a disease producing vascular thrombus with antiphospholipid antibody without association with autoimmune diseases as systemic lupus erythematosus. Retinal vein occlusion is a rare vascular manifestation in primary APS. We describe 2 cases of primary APS presenting with developing blurred vision. Each had central retinal vein occlusion and high titer of...

The primary antiphospholipid/anticardiolipin syndrome is a recently described entity wherein muli Rceived July 7. 1992. Accepted November 5, 1992. a Correspondence to Dr. D.O.B. 5okunbi, Division of Nephrology, Deportment of MdIcin#{149}, School of Medicine, H5C T-15, Room 020, SUNY at 5tony Brook, Stony Brook,NY 11794. 1046-6673/0401-0028503.00/0 .Joumal of the American Society of Nephrology C...

We report two cases of cerebral venous sinus thrombosis associated with an antibody to phospholipids, namely the lupus anticoagulant. Both patients later developed further immunologically mediated conditions. The importance of screening for the lupus anticoagulant in addition to anticardiolipin antibodies in this condition and the need for follow-up of such patients is discussed.

A case of adenocarcinoma of the lung, in which high titre anticardiolipin antibodies were associated with recurrent venous thromboses resistant to all forms of therapy, is described. It is suggested that such an autoimmune response may be a contributory factor in the para-neoplastic development of vascular thromboses.

Concept of autoimmune basis of infertility is still controversial, particularly regarding the presence of non-organ specific autoantibodies. Non-organ specific anticardiolipin (aCL) and antithyroglobulin (TgAt) antibodies were detected in infertile women. Both partners were evaluated according to the criteria of The American Society for Reproductive Medicine. All the results were normal in case...