In this second chapter on Acute Drugs Poisoning we deal with two groups of substances of great transcendence from the point of view of their use and morbidity/mortality. Within the group of analgesic-anti-inflammatory drugs we consider paracetamol and the salicylates, which are easily available to the population. With respect to the anticonvulsants, although they are barely involved in the ense...

Seizures and seizure-like activity may occur in patients experiencing aneurysmal subarachnoid hemorrhage. Treatment of these events with prophylactic antiepileptic drugs remains controversial. An electronic literature search was conducted for English language articles describing the incidence and treatment of seizures after aneurysmal subarachnoid hemorrhage from 1980 to October 2010. A total o...

Although anticonvulsant drugs are the mainstay of therapy for epilepsy, their mechanisms of action remain uncertain for several reasons. First, most anticonvulsant compounds have been shown to have multiple physiological, biochemical, and pharmacological actions. It has been difficult, therefore, to determine which specific drug actions produce clinical effects. Second, investigation has often ...