Bacillus species are promising producers of various compounds that have pronounced antimicrobial, antiviral and antitumor activities. Due to its GRAS status, subtilis represents an excellent candidate for the usage in plant pathogens biocontrol. In this research, evaluation antifungal metabolites biosynthesis by ATCC 6633 optimization glycerol-based medium composition, using response surface me...

Abstract Fimbristylis genus had commonly found as a dominant weed in the rice fields. The sedges have been identified one of invasive world and their undesirable presence disturb growth crop. secondary metabolites, on other hand, revealed that this plant is capable wide range biological activities. Therefore, study focused phytochemistry, antioxidant antifungal properties 2 weeds Fimbristylis. ...

Tea tree oil (TTO), a volatile essential oil, has been widely used as an antimicrobial agent. However, the mechanism underlying TTO antifungal activity is not fully understood. In this study, a comprehensive metabolomics survey was undertaken to identify changes in metabolite production in Botrytis cinerea cells treated with TTO. Significant differences in 91 metabolites were observed, includin...

Marine sponges, the sessile invertebrates of the Phylum porifera are invaluable tool in current research. They remain as a goldmine to chemist and pharmacologist due to its defensive weapons, the secondary metabolites. Endogenous peptides from marine sponges and associated microorganisms are promising lead compound for drug development. Some of the compounds are under clinical trials. These pep...

Agriculture-relevant microorganisms are considered to produce secondary metabolites during processes of competition with other micro- and macro-organisms, symbiosis, parasitism or pathogenesis. Many different strains of the genus Trichoderma, in addition to a direct activity against phytopathogens, are well-known producers of secondary metabolites and compounds that substantially affect the met...

Abstract: This is a systematic review of scientific articles reporting the biodiversity endophytic fungi isolated from endemic Cerrado plants in Brazil and exposes potential applications these microorganisms production known new metabolites. The “Portal de Periódicos” (CAPES), Science Direct, PubMed, Scielo, Biblioteca Virtual em Saúde (BVS) databases were used. A total 418 found using followin...

Deep-sea fungi, the fungi that inhabit the sea and the sediment at depths of over 1000 m below the surface, have become an important source of industrial, agricultural, and nutraceutical compounds based on their diversities in both structure and function. Since the first study of deep-sea fungi in the Atlantic Ocean at a depth of 4450 m was conducted approximately 50 years ago, hundreds of isol...

A screen for antifungal compounds from Lysobacter enzymogenes strain C3, a bacterial biological control agent of fungal diseases, has previously led to the isolation of heat-stable antifungal factor (HSAF). HSAF exhibits inhibitory activities against a wide range of fungal species and shows a novel mode of antifungal action by disrupting the biosynthesis of a distinct group of sphingolipids. We...

An indigenous Streptomyces isolate CTF9, exhibiting promising antifungal activity against Mucor miehei and Candida albicans in pre-screening studies, was investigated by cultivation in a 50-L fermenter and by subsequent isolation, purification, and structure elucidation of the active metabolites. Based on the morphological, biochemical, and physiological characterization, as well as the 16S rRN...

The genus Allochrusa (Caryophyllaceae) comprises nine species, which are native to Central Asia, Turkey, Iran, Afghanistan, and the Caucasus. They have been used in folk medicine preparation of various sweets detergents, especially Asian countries. A diversity secondary metabolites has reported from Allochrusa, including triterpene glycosides, ecdysteroids, flavonoids, volatile compounds, fatty...