The essential oils, isolated by hydrodistillation from the leaves, seeds and rhizomes of Heracleum sprengelianum (Wight and Arnott), collected from the Western Ghats of Peninsula India, were analyzed by gas chromatography (GC) and gas chromatography coupled to mass spectrometry (GC–MS). The antioxidant property of these oils was tested, with and without peroxidation inducer, through the egg yol...

Introduction: Paracetamol is a potent hepatotoxin and may cause severe acute hepatocellular injury. The present study was intended to assess the hepatoprotective potential of Caralluma umbellata Haw. (Asclepiadaceae) against paracetamol induced hepatotoxicity in vitro and in vivo experimental models. Methods: Preliminary analysis for antioxidant and hepatoprotective property was evaluated for m...

The present study investigates a concentration-dependent assessment of scavenging property and antioxidant activity in the extracts of Emblica officinalis Gaertn. syn. Phyllanthus emblica L. fruit using various in vitro assays. A correlation of aqueous and ethanolic extract of Emblica fruit along with different known standards for its antioxidative properties was made by performing assays like ...

The alcoholic extract of stem of E. pursaetha (PSE, 30, 100, 300 mg/kg body weight, po for 7 days) showed hepatoprotective activity against CCl4 (2 mL/kg body weight, ip)-induced hepatotoxicity. The extract exhibited a significant dose-dependent hepatoprotective effect comparable to standard drug silymarin, by preventing increase in serum levels of alanine aminotransferase, aspartate aminotrans...

Alcoholic extract of pericarp showed significant protection against FeSO4 induced lipid peroxidation, as compared with whole native nut and seeds. Mechanism of action may be through metal chelation or activation of endogenous antioxidant enzymes, because the extract did not show hydroxyl and super oxide anion scavenging property. Further in vitro experiments against FeSO4, it did not maintain t...

The antioxidant and antityrosinase activities of the water extract of Flemingia macrophylla root (WEFM) were investigated. The results showed that WEFM exhibited radical scavenging and reducing activities, as well as ferrous ion chelating property. In addition, WEFM also protected phospholipids against oxidation, indicating that WEFM could protect biomolecules from oxidative damage. Meanwhile, ...

In the present study the methanol extract of Gynocardia odorata roxb (MEGO) against acetaminophen induced hepatotoxicity and antioxidant activity in Wistar albino rats was analysed. The methanol extract of G.odorata roxb (200, and 400 mg/kg body weight) was administered orally to two groups of rats (six animals per group) in order to evaluate the protective effect of the extract in rats. The ot...

Aims: To evaluate the anti-inflammatory and antioxidant activity of methanolic root extract of onosma hispidum (Ratanjot) by in-vitro methods. Methods: DPPH free radical and ABTS radical scavenging activity estimation with total phenolic and flavonoid content methods were used to evaluate antioxidant activity while egg albumin denaturation method and HRBC membrane stabilization methods were use...

The well known medicinal plant, Cichorium intybus L. (Asteraceae) contains dietary oligofructose compounds which have beneficial effect on carbohydrate and lipid metabolism, other compounds e.g. polyphenol type derivatives could be responsible for the antioxidant properties reported in several studies before. Male Fischer rats were kept on normal and lipid rich diet supplemented with chicory ex...