BACKGROUND Oxidative stress has been known for having a key role in pathogenesis of many diseases. The aim of this study was to investigate the oxidative stress and also the relationship between antioxidant system statuses and lung function in patients with COPD and smokers and non-smokers subjects. METHODS Thirty subjects with COPD, 30 smokers, and 30 healthy non-smokers participated in this...

In this review, we disclose a selection of serum/plasma biomarkers of (anti)oxidant status related to nutrition, which can be used for measurements in large-scale epidemiological studies. From personal experience, we have come to the following proposal of a set of biomarkers for nutritional intake, (anti)oxidant status, and redox status. We have selected the individual antioxidant vitamins E an...

Dear Sir: In a recent issue of the Journal, Dragsted et al (1) investigated whether fruit and vegetable intake affects biomarkers of oxidative stress or antioxidant defenses. They conducted a well-designed, 25-d, randomized, partly blinded intervention trial. Some of their conclusions related to an apparent lack of effect on markers of total antioxidant capacity [TAC; namely, the ferric-reducin...

BACKGROUND & OBJECTIVES Rheumatoid arthritis (RA) is a debilitating, chronic multisystem disease with an unknown etiology. Recent findings indicate that increased oxidative stress and/or defective antioxidant status contribute to the etiology of RA. The present study was undertaken to examine the oxidant and antioxidant systems in patients with RA and healthy controls. METHODS Twenty two pati...

Although it is well known that physical training ameliorates brain oxidative function after injuries by enhancing the levels of neurotrophic factors and oxidative status, there is little evidence addressing the influence of exercise training itself on brain oxidative damage and data is conflicting. This study investigated the effect of well-established swimming training protocol on lipid peroxi...

INTRODUCTION Coronary artery disease is caused by the additive and interactive effects of inherited and environmental factors. Substantial evidence shows that reactive oxygen species (ROS) play a vital role in the aetiopathogenesis of atherosclerosis. Our study has been designed to evaluate the oxidative stress due to ROS and assess the antioxidant protection against ROS, in addition to the maj...

Oxidative stress is involved in a variety of diseases. Prospective studies investigating the relationship between oxidative stress biomarkers and the status and development of colorectal cancer (CRC) are scarce; previous studies have failed to establish a relationship between the serum total oxidant/antioxidant status and CRC. Therefore, we compared the total serum oxidant/antioxidant levels of...

Physical training is known to induce a biochemical adaptive response which might require an increase in the ingestion and/or the absorption of micronutrients. A question that is still being raised is whether acute or chronic exercise modifies antioxidant requirements. First, the present review brings to light the most crucial studies on the topic. Second, it interprets the established relations...