background: optimal timing and mode of treatment for patients with coarctation of the aorta ( coa ) remain controversial, particularly in children. surgery, balloon dilatation, and stent implantation have all proven effective in the treatment of moderate or severe obstruction. the aim of this study was to investigate the complications of coa stenting angioplasty in pediatric patients. methods: ...

over the last 50 years, significant progress has been made in the surgical repair of thoracoabdominal aortic aneurysms (taaa).   improvements in perioperative care and surgical techniques have resulted in reductions in complication and mortality rates. adjunctive use of distal aortic perfusion and cerebrospinal fluid drainage has been especially helpful, reducing the incidence of neurological d...

background: the p ulsatility index (pi) shows continuous blood flow to the end organs and is a significant factor believed to decrease in aortic coarctation. correction of this factor is of great importance in the treatment of stenotic lesions of the aorta. however, there are minimal data regarding the trend of changes in the pi after stent implantation. furthermore, the association between the...

Stanford type A acute aortic dissection (AAD) is a very rare complication, with potentially lethal consequences in pregnancy. In fact, pregnancy has been regularly associated with the possibility of aortic. dissection in almost half of young women. Herein, we present the case of a 38-year-old woman in her 37th week of pregnancy. The patient’s medical history was indicative of G4L2Ab1(4 gestaiti...

BACKGROUND AND PURPOSE Visit-to-visit and day-to-day variability in systolic blood pressure (SBP) are associated with an increased risk of stroke, more strongly than variability on 24-hour ambulatory BP monitoring, but underlying physiological mechanisms are unclear. We related potentially relevant physiological characteristics to beat-to-beat, ambulatory, and day-to-day BP variability to ident...

a ruptured sinus of valsalva aneurysm rarely accompanies the aortic and tricuspid valve endocarditis. a 36-year-old woman presented with low-threshold dyspnea on exertion and fever. transthoracic and transesophageal echocardiography showed a ruptured noncoronary sinus of valsalva aneurysm with large vegetations on the tricuspid and aortic valves, resulting in moderately severe tricuspid regurgi...

Perivascular adipose tissue (PVAT) mediates buffering of vasoconstriction through activation of endothelium-derived factors. We hypothesized that the PVAT of Dahl salt-sensitive (Dahl SS) rats has reduced ability to buffer vasoconstriction. Vascular reactivity experiments were performed on aortic rings with PVAT intact (+PVAT) or removed (-PVAT), and endothelium intact (+ENDO) or removed (-ENDO...

AIMS Platelets have a fundamental role in atherothrombosis, but their role in early atherogenesis is unclear. The P2Y12 receptor is responsible for amplifying and sustaining platelet activation and P2Y12 inhibition is crucial in modulating the vessel wall response to injury. We therefore examined the role of platelet vs. vessel wall P2Y12 in early atherogenesis and considered the use of P2Y12 a...

the bicuspid aortic valve is known to be the most common congenital cardiac malformation, with an approximate incidence rate of 1-2% in the general population. most patients are unaware of the disease until the onset of infective endocarditis, which is a life-threatening complication that may affect a heart valve or other cardiac structures at the site of endothelial damage. a 22-year-old man p...