Aneurysms are common in the abdominal and thoracic regions of the aorta. While generally asymptomatic, progression of aneurysms is associated with the devastating consequences of aortic rupture. Current therapeutic options to prevent rupture are restricted to surgical repair, as there remains a lack of validated pharmaceutical approaches. Absence of proven medical therapies may be a consequence...

This video contains rupture of a paravisceral penetrating aortic ulcer treated by fenestrated endovascular repair with the modified preloaded system. eyJraWQiOiI4ZjUxYWNhY2IzYjhiNjNlNzFlYmIzYWFmYTU5NmZmYyIsImFsZyI6IlJTMjU2In0.eyJzdWIiOiI1YjkyY2IzODc2ZmIzOTliY2Q3NWMyMTJjZWUzZjAxOCIsImtpZCI6IjhmNTFhY2FjYjNiOGI2M2U3MWViYjNhYWZhNTk2ZmZjIiwiZXhwIjoxNjg4NTQ1MTczfQ.nx5l_536gK8YfLzzhTFfK4NdYiUOUk47s4yP...

We report the case of a 71-year-old man hospitalized for acute heart failure. Transthoracic and transesophageal echocardiography showed mitral valve aneurysm (MVA) rupture and severe mitral regurgitation. No vegetations but significant aortic regurgitation were also observed. MVA perforation is a rare life-threatening condition that typically occurs as a complication of endocarditis but may als...

A 54 years old male with undiagnosed chronic calcific degenerative aortic valve incompetence presented with acute left anterior chordae tendinae rupture resulting in severe left heart failure and cardiogenic shock. He was successfully treated with emergency double valve replacement using mechanical valves. The pathogenesis of acute rupture of the anterior chordae tendinae, without any evidence ...

Background Thoracic aortic aneurysm (TAA) is life-threatening and requires close follow-up to prevent aortic dissection and/or rupture. Aortic wall stiffness and luminal size are considered to be coupled. Regional aortic wall stiffness in patients with TAA is unknown. Evaluation of regional stiffness may supplement monitoring for prediction of progressive aortic dilatation. Aortic Pulse Wave Ve...

Aortic aneurysm (AA) is a life threatening condition. Large AA carries a substantial risk of rupture. Observational studies have reported a 14.1% annual incidence rate of aortic rupture. Once the aorta has reached a diameter of 6 cm the risk of rupture increases in proportion to the aortic diameter (Elefteriades, 2002). The 5-year cumulative risk of rupture has been estimated to be 31 % among a...

BACKGROUND Current practice guidelines recommend surgical repair of large thoracic aortic aneurysms to prevent fatal aortic dissection or rupture, but limited natural history data exist to support clinical criteria for timely intervention. METHODS AND RESULTS Of 3247 patients with thoracic aortic aneurysm registered in our institutional Thoracic Aortic Center Database, we identified and revie...