In patients with upper gastrointestinal bleeding (UGIB), identifying those with esophageal variceal hemorrhage prior to endoscopy would be clinically useful. This retrospective study of a large cohort of patients with UGIB used logistic regression analyses to evaluate the platelet count, aspartate aminotransferase (AST) to platelet ratio index (APRI), AST to alanine aminotransferase (ALT) ratio...

Abstract Background We evaluated the validity of some non-invasive scores and ultrasound findings to predict fibrosis steatosis in a cohort NAFLD patients who underwent liver biopsy. Ninety-seven were enrolled classified into NASH (66) simple groups (31) based on ROC curves constructed for Fibrosis-4 index (FIB4), aspartate aminotransferase platelet ratio ( APRI), score (NFS) prediction, also (...

Background Preeclampsia (PE) is one of the highest-risk pregnancies and a complicated condition that occurs in 2% to 8% associated with markers systemic inflammatory response (SIR). In this study, we aimed determine role these predicting PE. Methodology A total 300 women singleton cephalic presentation were included study. Normotensive pregnant (n = 149) who met criterion as control group Pregn...

Amaç: Son yıllarda kronik hepatit B’li (KHB) hastalarda fibrozisi değerlendirmek amacıyla noninvaziv tanı yöntemleri üzerinde pek çok çalışma yapılmıştır. Ancak halen karaciğer biyopsisi altın standart olarak kabul edilmektedir. Bu çalışmada KHB hastalarının biyopsi sonuçlarını ve non-invaziv fibrozis skorlama bulgularını karşılaştırmayı bunların ışığında tedaviye başlama açısından biyopsiyi de...

Juvenile idiopathic arthritis is the most common form of in children and adolescents. Methotrexate mainstay juvenile treatment. well known to cause serum aminotransferase elevations, longterm therapy has been linked development fatty liver disease, fibrosis even cirrhosis. The aim study was assess non-invasive indexes adolescents with treated methotrexate. Materials methods: A total 68 were enr...

Abstract To evaluate the accuracy of biomarkers for early diagnosis biliary atresia (BA) and prognostic stratification after Kasai portoenterostomy (KPE). We conducted a systematic review PubMed, Web Science, Embase, Scopus OVID English literature reporting BA published before August 2020. Screening, data extraction, quality assessment were performed in duplicate. A total 51 eligible studies in...

conclusions nx-dcp correlated positively with fibrosis stage and could discriminate well between hcv-related patients with or without significant fibrosis. moreover, nx-dcp had a similar predictive ability to the abovementioned models, and thereby could be a new noninvasive prediction tool for fibrosis. results increase in serum nx-dcp was significantly related to increase in fibrosis stage (p ...

BACKGROUND Cystic fibrosis-related liver disease (CFLD) is present in up to 30% of cystic fibrosis patients and can result in progressive liver failure. Diagnosis of CFLD is challenging. Non-invasive methods for staging of liver fibrosis display an interesting diagnostic approach for CFLD detection. AIM We evaluated transient elastography (TE), acoustic radiation force impulse imaging (ARFI),...

AIM To evaluate the diagnostic performance of angiotensin-converting enzyme (ACE) on significant liver fibrosis in patients with chronic hepatitis B (CHB). METHODS In total, 100 patients with CHB who underwent liver biopsy in our hospital were enrolled, and 70 patients except for 30 patients with hypertension, fatty liver or habitual alcoholic consumption were analyzed. We compared histologic...

BACKGROUND Aspartate aminotransferase-to-platelet ratio index (APRI), aspartate aminotransferase-to-alanine aminotransferase ratio (AAR), FIB-4, fibrosis index (FI), and King scores might be alternatives to the use of upper gastrointestinal endoscopy for the diagnosis of esophageal varices (EVs) in liver cirrhosis. This study aimed to evaluate their diagnostic accuracy in predicting the presenc...