Objective: The present study on garlic cloves (Allium sativum) belongs to family Amaryllidaceae has been focused. This is a natural medicinal plant used for disease preventions against all kinds of internal infections. Preliminary screening of phytochemicals has found plenty of secondary metabolites which are present in garlic cloves. Their functional groups and mineral compositions, the potent...

The ability of some pathogenic bacteria to develop antibiotic resistance has become a global health challenge, and there is an increasing rate against the available drug. This study aimed determine inhibitory effect Allium sativum (Garlic) Zingiber officinale (Ginger) extracts on clinical bacteria. Four different concentrations (125mg/ml, 250mg/ml, 500mg/ml, 1000mg/ml) each extract were tested ...

Objective: Garlic is a plant has been used as a flavor, and anti-microbial and anti-diarrheal agent. Infectious bronchitis virus (IBV) is a coronavirus. The available vaccines against IBV cannot cover new variants. This study evaluated the inhibitory effects of garlic extract on IBV.  Materials and Methods: The constituents of garlic extract were detected by gas chromatography. This study was d...

In the present study, the effect of garlic (Allium sativum) extract on ischemic preconditioning and ischemia-reperfusion induced cardiac injury has been studied. Hearts from adult albino rats of Wistar strain were isolated and immediately mounted on Langendorff's apparatus for retrograde perfusion. After 15 minutes of stabilization, the hearts were subjected to four episodes of 5 min ischemia, ...

Possible effects of aqueous garlic (Allium sativum Linn.) and red clover (Trifolium pratense Linn.) extracts on adenosine deaminase (ADA) activities were investigated in cancerous and non-cancerous human liver tissues and results were compared with those of Fludarabine, a known ADA inhibitor. Ten cancerous and 10 non-cancerous adjacent liver tissues were obtained from patients with metastatic t...

BACKGROUN/OBJECTIVES Although studies have revealed that black garlic is a potent antioxidant, its antioxidant mechanism remains unclear. The objective of this study was to determine black garlic's antioxidant activities and possible antioxidant mechanisms related to nuclear factor erythroid 2-like factor 2 (Nrf2)-Keap1 complex. METHODS/MATERIALS After four weeks of feeding rats with a normal...

Studies suggest that garlic (A. sativum) improves memory dependent on the hippocampus. However, the effect of ethanol garlic extract on hippocampus Na+/K+ ATPase, Ca2+ ATPase, and glutamine synthetase (GS) activities as possible mechanisms in memory improvement in diabetic Wistar rats has not been reported. Twenty-four male Wistar rats weighing 200-250 g were divided into three groups with 8 ra...

BACKGROUND Garlic is widely promoted as a cholesterol-lowering agent, but efficacy studies have produced conflicting results. Garlic supplements differ in bioavailability of key phytochemicals. We evaluated the effect of raw garlic and 2 commonly used garlic supplements on cholesterol concentrations in adults with moderate hypercholesterolemia. METHODS In this parallel-design trial, 192 adult...