Microbes have been catapulted into the spotlight again by recent studies showing that uniquely modern phenomena, like jet lag and artificial sweeteners, can affect health by altering the microbiome (Suez et al., 2014; Thaiss et al., 2014). However, even as the nature of our current relationship with bacteria unfolds, DNA sequencing and proteomic approaches are giving us a fascinating glimpse in...

The suspected bladder tumor promoters saccharin and cyclamate reversibly inhibited nerve growth factor-induced neurite outgrowth in embryonic chick sensory ganglia, and active concentrations of these artificial sweeteners inhibited binding of 125l-labeled mouse submaxillary gland nerve growth factor as well. The skin tumor promoter phenol also reversibly in hibited neurite outgrowth, while comp...

EFSA is implementing evidence-based risk assessments for the re-evaluation of certain sweeteners. The aim this work was to ensure that, as part preparatory done by support its Panel on Food Additives and Flavourings (FAF) in reaching conclusions safety permitted food additives, relevant information environmental risks associated with use artificial sweeteners are identified. In context process ...

Alternative sweeteners are widely advocated and used. However, there is insufficient scientific information to determine whether alternative sweeteners aer of value in the management of diabetes, either in improving dietary adherence or in contributing to the achievement or maintenance of a lower body weight. Each of the available sweeteners has advantages and disadvantages; no one is preferred...

Riboflavin-binding protein (RBP) is well known as a riboflavin carrier protein in chicken egg and serum. A novel function of RBP was found as a sweet-suppressing protein. RBP, purified from hen egg white, suppressed the sweetness of protein sweeteners such as thaumatin, monellin, and lysozyme, whereas it did not suppress the sweetness of low molecular weight sweeteners such as sucrose, glycine,...

To understand the functional similarities of fly and mammalian taste receptors, we used a top-down approach that first established the fly sweetener-response profile. We employed the fruit fly Drosophila melanogaster, an omnivorous human commensal, and determined its sensitivity to an extended set of stimuli that humans find sweet. Flies were tested with all sweeteners in 2 assays that measured...

the effects of some synthetic sweeteners on the rheological and physical properties of guar gum in dilute solutions were investigated.measurements include the determination of intrinsic viscosity and the particle size, surface weighted mean [d3, 2], volume weighted mean [d4,3] and specificsurface area ofguar gum andsyntheticsweeteners mixtures. the concentration of these sweeteners were 0, 0.1,...