1H NMR spectroscopy was used to monitor the reactions of an arylidene 2-thiohydantoin derivative, 3-((phenylmethylene)amino)-2-thioxo-4- imidazolidinone (3), with PdCl2, cis-[PdCl2(dmso-S)2] and K2[PdCl4] in DMSO-d6 order elucidate reaction kinetics mechanism. The derivative 3 formed cis-[Pd(3-N,S)(dmso-S)2]+ complex (5) PdCl2 cis-[PdCl2(dmso-S)2], while no observed. A two-step mechanism for ci...

Abstract: Background: Diabetes mellitus, a lifestyle related global health crisis has rapidly engulfed the entire world. In past, various thiazolidinedione derivatives have been successfully developed for management of diabetes. Materials and Methods: Herein, we report synthesis, characterization (1H-NMR, 13C-NMR mass spectroscopy methods) novel aryl sulfonyloxy-5-arylidene thiazolidine-2,4-dio...