BACKGROUND The Adult Social Care Outcomes Toolkit (ASCOT) measures social care related quality of life (SCRQoL) and can be used to measure outcomes and demonstrate impact across different social care settings. This exploratory study built on previous work by collecting new inter-rater reliability data on the mixed-methods version of the toolkit and exploring how it might be used to inform pract...

FOREWORD This guidance has been developed for use in the IAEA's Safety Culture Services, which provides support to Member States in their efforts to develop a sound safety culture of their organizations. It will be of particular use in seminars and training workshops that are part of these services. Much of the information in this publication reflects the approach the IAEA has adopted to assist...

BACKGROUND Relative risk reduction with statin therapy has been consistent across nearly all subgroups studied to date. However, in analyses of 2 randomized controlled primary prevention trials (ASCOT [Anglo-Scandinavian Cardiac Outcomes Trial-Lipid-Lowering Arm] and JUPITER [Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin]), statin therapy led ...

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OBJECTIVE To evaluate the effect of comorbidity and other risk factors on postoperative mortality and morbidity in patients undergoing major oesophageal and gastric surgery. DESIGN Multicentre cohort study with data on postoperative mortality and morbidity in hospital. DATA SOURCE AND METHODS The ASCOT prospective database, comprising 2087 patients with newly diagnosed oesophageal and gastr...

BACKGROUND The first carpometacarpal joint (CMCJ) in the hand is a commonly affected joint by osteoarthritis. It causes significant thumb base pain, limiting functional capacity. Microfracturing and application of autologous stem cells has been performed on large joints such as the knee but has never been evaluated for use in the smaller joints in the hand. Our aim was to determine the potentia...

Hypertension, defined as systolic blood pressure (SBP) greater than 140 mm Hg or diastolic blood pressure (DBP) greater than 90 mm Hg, remains a significant problem that results in increased risk of cardiovascular disease [1]. Despite heightened recognition of this problem, less than 40% of patients are at their goal blood pressure (BP) [2]. There are multiple pharmacologic treatments for hyper...

One of the principal problems en route to a fusion reactor is that of insufficient plasma confinement, which has lead to both theoretical and experimental research into transport processes in the parameter range relevant for fusion energy production. The neoclassical theory of tokamak transport is well-established unlike the theory of turbulence driven anomalous transport in which extensive pro...

Abstract In Wendelstein 7-X (W7-X), a new ion cyclotron resonance heating (ICRH) antenna will be commissioned during the operational campaign OP2.1. The have to sustain power loads not only from thermal plasma and radiation but also fast ions. Predictive simulations of fast-ion components are therefore important establish safe limits. this work, W7-X neutral beam injection (NBI) system ICRH was...