Advanced heart failure has been traditionally treated via either heart transplantation, continuous inotropes, consideration for hospice and more recently via left ventricular assist devices (LVAD). Heart transplantation has been limited by organ availability and the futility of other options has thrust LVAD therapy into the mainstream of therapy for end stage heart failure. Improvements in tech...

It is known that various electromagnetic methods have been investigated for the short-term earthquake p ediction. To make inte grated inves iga ion of these methods and find some correlations of earthquakes and various phenomenon, an integrated database system for short-term earthquake p ediction is needed. In this pape , we present the design of an integrated database system for the ICA (Indep...

A hydraulic loop, which simulates pressure/flow response of the human circulatory system, is needed to bench test the various versions of rotary left ventricular assist devices (LVADs). This article describes the design of such a loop and the simulated response of different physiological states, such as a healthy person in sleep, rest, and mild physical activity, and in different pathological s...

Miniaturization of laboratory instrumentation is becoming critical in achieving the speed and throughput required by the current revolutionary progress in biology. This mini review critically summarizes the present status of microfluidic devices designed for use in mass spectrometry.

Results Our data show preoperative values including age [67.1 y+5.0 y] and INTERMACS classification [range 2-4]. The indication for DT includes old age, compliance problems, and severe comorbidities. Outcome data demonstrate a low 30-day mortality in elective DT patients (100% survival). Mean follow up after permanent Heartware implantation was in average 544 days (range, 160-1512). 1 year surv...

BACKGROUND Proportional assist ventilation+ (PAV+) delivers airway pressure (P aw) in proportion to patient effort (P mus) by using the equation of motion of the respiratory system. PAV+ calculates automatically respiratory mechanics (elastance and resistance); the work of breathing (WOB) is estimated by the ventilator. The accuracy of P mus estimation and hence accuracy of the delivered P aw a...

Methods Over 39 consecutive months, 51 cardiomyopathy patients were referred for standard 3D CMR(1·5T,GE) to interrogate the LV pattern, distribution and extent of DHE (MultiHance, Princeton, NJ). Inclusion criteria were met in 21 patients. DCM were categorized into: 1) +midwall Stripe 2)-Stripe groups. Major adverse clinical events (MACE), mortality, need for LV assist device (LVAD), and urgen...

A large number of people are affected with heart failure annually and require left ventricular assist device placement as a bridge to heart transplant or as destination therapy. When these devices become infected, it is a challenge to eradicate the infection. Failure ultimately results in a significant morbidity and mortality. Source control along with debridement and antibiotics can eradicate ...

In patients with end-stage left ventricular (LV) heart failure who receive LV assist device (LVAD) implantation, right ventricular (RV) failure represents a possible critical complication that heavily affects morbidity and mortality. Several clinical, laboratory, hemodynamic, and echocardiographic variables have been found to be associated with RV failure occurrence after surgery. Different mod...