Since the development of cardiac surgery, defects of the atrial septum have been recognized with increased frequency. During the past 15 years, various surgical techniques have been used, and even to-day the surgical treatment of this lesion is not uniform. In 1948, Murray first closed an atrial septal defect, suturing together the anterior and posterior atrial walls in the septal plane. S0nder...

Five patients with an ostium primum type of atrial septal defect were studied by clinical and laboratory methods and the diagnosis was verified either at the time of open-heart surgery and/or at autopsy. The atrioventricular valves formed the floor of the defect and were deformed in 4 of the 5 patients. Mitral insufficiency was present as a result of this valvular deformity in these four patien...

Five patients with an ostium primum type of atrial septal defect were studied by clinical and laboratory methods and the diagnosis was verified either at the time of open-heart surgery and/or at autopsy. The atrioventricular valves formed the floor of the defect and were deformed in 4 of the 5 patients. Mitral insufficiency was present as a result of this valvular deformity in these four patien...

Forty patients with simple atrial septal defect had left ventriculograms using cineangiography and/or Elema or Sircam still films. All had open heart surgery and careful scrutiny of the mitral valve by experienced surgeons. Prolapse of the posterior cusp was diagnosed from angiography in 28 patients but was confirmed at operation in only 5. Another 5 had a different mitral valve abnormality and...

Assessment of the complex relations between pressure and volume in the right atrium has been hampered in the past by difficulties in the measurement of atrial volume. Accordingly, in the present study the dynamics of right atrial pressure-volume relations were examined (with the use of an impedance catheter to measure right atrial volume) in patients with and without an atrial septal defect. Ri...

P ROPER elinical anialysis of the secondll heart sound has oily recently been emphasized.1 An ullderstalldill(r of the normal second heart sound has increased the diagnoslie usefulness of its variations in congenital and acquired heart disease. In atrial septal (lefeet, as emphasized by Wood,( the aortic aid pulmnonic coniponelits of the second heart sou]d(l are not o0ly widely separated, but t...

BACKGROUND AND OBJECTIVES This study aims to compare the characteristics, effectiveness and results of transcatheter closure of atrial septal defect between children, adolescents, and adults. SUBJECTS AND METHODS In this study, 683 patients who underwent atrial septal defect closure in the last 10 years were divided into three groups: children (age <12), adolescents (age 12 to 16), and adults...

L acerations or tears of the interatrial septum are a recognized complication of mitral valve replacement surgery; however, the first report of iatrogenic Lutembacher's syndrome was by Dr. John Ross Jr. and colleagues from the National Institutes of Health.1 Their series included three patients who had acquired mitral stenosis and developed a persistent atrial septal defect after transatrial se...