BACKGROUND Classic Ehlers-Danlos syndrome (cEDS) is a rare autosomal dominant connective tissue disorder that is primarily characterized by skin hyperextensibility, abnormal wound healing/atrophic scars, and joint hypermobility. A recent study demonstrated that more than 90% of patients who satisfy all of these major criteria harbor a type V collagen (COLLV) defect. METHODS This cohort includ...

background: atrophic vaginitis is a disease, which affects up to 50% of postmenopausal women. this study compared the effectiveness and user-friendliness of vagifem (an estradiol vaginal tablet) and vaginal estrogen cream in the treatment of atrophic vaginitis. materials and methods: one hundred and  sixty postmenopausal women with symptoms of atrophic  vaginitis were randomly divided into two ...

In a young woman, the differential diagnosis of ulcerated skin lesions on the lower limbs that heal leaving atrophic scars should include vasculitis and occlusive vasculopathy. Cutaneous polyarteritis nodosa (CPN) is characterized by the presence of painful nodules that typically develop on the lower limbs, frequently ulcerate, and usually heal without residual hyperpigmentation. Its diagnosis ...

introduction:oral lichen planus(olp)is a chronic mucocutaneus disease with an immunological etiology. this study was conducted to evaluate the effect of cedar honey in treatment of erosive- atrophic olp.materials and methods: thirty patients with confirmed clinical and histopathologic of olp participated in a randomized clinical trial in mashhad dental school.patients were randomly allocated in...

Although the healing means 2 types of biological mechanisms that seem to be "pathologic", the swell and the granulations are a normal process in the biology of the human being, representing two systemic functions: the adaptation and the morphogenesis. There is a pathological healing in which the fundamental healing phenomenon is deviated from the normal. There are three variable parameters resp...

BACKGROUND: Acne is a chronic inflammatory skin disease of multifactorial nature that affects more than 80% adolescents and one the top 10 most common diseases in world. Currently, dermatologists have various techniques for correction postacne scars: from minimally invasive hydroxy acid peels to surgical excision scar tissue. One effective, affordable, at same time safe treatment methods micron...

BACKGROUND Surgical scars are crucial cosmetic problem, especially when in exposed areas such as the anterior neck following thyroidectomy. OBJECTIVE To evaluate the impact of post-thyroidectomy scars on quality of life (QoL) of thyroid cancer patients and identify the relationship between scar characteristics and QoL. METHODS Patients with post-thyroidectomy scars on the neck were recruite...

purpose our study aims to investigate the effectiveness of other treatment methods for burn related scarring and to determine the possibility of their routine administration in similar clinical settings. methods through a prospective study, 66 patients were enrolled to receive either the conventional pressure garment therapy (pgt) and silicone (control group) or exercise and physiotherapy (case...