Recently, Laia Tolosa and colleagues from Valencia University have published a study how to identify compounds that cause hepatotoxicity due to compromising mitochondrial functions (Tolosa et al., 2015). The authors used a set of fluorescent probes for imaging: HepG2 cells were loaded with Hoechst 33342 for cell number determination, cell viability was determined with propidium iodid and Mitotr...

Risk assessment of nanomaterials represents one of the cutting-edge topics in toxicology (Zhao et al., 2014; Lucafo et al., 2013; Fadeel et al., 2013; Kroll et al., 2012; Kim et al., 2012; Hadrup et al., 2012; Lange and Obendorf, 2012; Xu et al., 2013). Numerous nanomaterial containing consumer products have already been introduced on the market, including textiles, sunscreens, paints, car tyre...

Infectious ovine epididymitis affects rams worldwide, and it is considered to be one of the most important infectious diseases (Poester et al., 2013). Brucella ovis is one of the most important infectious agents associated with this disease, which may also be due to Histophilus somni infection, as well as other organisms (DíazAparicio et al., 2009; Poester et al., 2013; Moustacas et al., 2014)....

Abstract. In this paper, we introduce the concept of partial cone b-metric spaces as a generalization of partial metric, cone metric and b-metric spaces and establish some topological properties of partial cone b-metric spaces. Moreover, we also prove some common fixed point theorems for cyclic contractive mappings in such spaces. Our results generalize and extend the main results of Huang and ...

Cancer is the third most common cause of death following cardiovascular disease and accident (Mohebbi et al., 2008; Moradpour and Fatemi, 2013) and gastrointestinal (GI) cancers are the most frequent cancers among males and second to females’ breast cancer in Iran (Mohebbi et al., 2011). The epidemiological characteristic of upper GI cancer has markedly changed over recent decades so that oesop...

There is great interest in how pattern separation and pattern completion in the hippocampus contribute to its functions in memory and spatial function (Giocomo et al. 2011; Jezek et al. 2011; Leutgeb et al. 2007; McHugh et al. 2007; Nakashiba et al. 2012; Nakazawa et al. 2002, 2003; Wills et al. 2005), and among those who have made many contributions in this area are Ray Kesner and his colleagu...

The reply by Petron et al. [2012a] to my comment, Levi [2012], on their paper, Petron et al. [2012], defends their original conclusion: fugitive emissions in an area that they observed in 2008 were likely larger those indicated by previous estimates. The reply also claims to have now better characterized the uncertainties in their and my approaches. In particular, they question the representati...

Endometrial cancers are the most common gynecologic cancers of United States (U.S.), with over 35000 cases diagnosed each year (Duong et al., 2011). The incidence is on the rise because of obesity epidemic. Current management includes surgery alone for early endometrial cancers and additional post-operative radiotherapy (Patel et al., 2012) (Koskas et al., 2011) and chemotherapy (Wright et al.,...