A 48-year-old man, a heavy smoker and drinker, came to the emergency department complaining of pain, redness, and vision loss in his left eye (Figure A). Physical examination revealed a body temperature of 38.7 8C and hyperemic left conjunctiva. His oral hygiene was clearly poor and he was missing a number of teeth. Auscultation disclosed the presence of a systolic murmur at the left sternal bo...

Gram-positive cocci are the most common pathogens in severe human eye infections. Streptococcal endophthalmitis is a devastating infection, and intravitreal antibiotic therapy is limited by retinal toxicity. Because few systemic antistreptococcal antibiotics penetrate into the vitreous, sparfloxacin, a newer quinolone with improved antistreptococcal activity, might be of interest. We therefore ...

Endophthalmitis is a devastating eye condition that can lead to permanent visual loss or even loss of the eye. It can occur from an immune mediated response to an antigen (sterile endophthalmitis) or most commonly from an infectious cause. Infectious endophthalmitis can be classified broadly into endogenous and exogenous. Endogenous endophthalmitis occurs from hematological spread in the settin...

Cephaloridine is a wide-spectrum antibiotic derived from cephalosporin and, despite similarities to penicillin, it can be used in the treament of infections in penicillin-sensitive patients. Riley, Boyle, and Leopold (I968) and Records (I969) have reported the intraocular penetration of cephaloridine into the aqueous after intramuscular and intravenous administration, and Moll, Crawford, and Mc...

PURPOSE To report a case of endogenous endophthalmitis due to Aeromonas hydrophila in a patient with distal common bile duct carcinoma and biliary sepsis. METHODS A 72-year-old woman with distal common bile duct carcinoma, obstructive jaundice, diabetes mellitus, and hypertension had a 1-day history of blurred vision, redness, and eye discharges in the right eye. An ophthalmic examination sho...

Endophthalmitis is a rare but severe form of ocular inflammation due to infection of the intraocular cavity that can lead to irreversible visual loss if not treated properly and timely. It can be classified as exogenous or endogenous based on the transmission route of the infectious source. Exogenous endophthalmitis occurs when infecting organisms gain entry into the eye via direct inoculation,...