OBJECTIVE To identify the microbiota communities in the vaginal tracts of healthy Mexican women across the pregnancy. METHODS Vaginal swabs were obtained during the prenatal visit of women from all trimesters (n = 64) of healthy pregnant women of Mexico City. DNA was isolated from each sample, and PCR-DGGE and sequencing of 16S rRNA gene fragments were used to identify the bacterial communiti...

Preterm delivery (PTD) is the leading cause of infant morbidity and mortality. Epidemiological association between PTD and various bacteria that are part of the vaginal microflora has been reported. Bacterial vaginosis is believed to be a risk factor for preterm delivery. The aim of the present study is to investigate the association between bacterial vaginosis, cervicovaginal fetal fibronectin...

OBJECTIVE During pregnancy cytokines and inflammatory mediators stimulate the expression of prostaglandin, the levels of which determine the onset of labor. The aim of this work was to study interleukin IL-1beta, IL-6 and IL-8 levels in the vaginal discharge, serum and urine of pregnant women with genitourinary infection before and after specific treatment. One hundred and fifty-one patients we...

Vaginosis is the most common infection in women of child bearing age. Infections are very common with more than 90 million cases of bacterial vaginosis (BV) worldwide per annum. This study was conducted to assess the efficacy of probiotics as a supplement along with metronidazole in treatment of vaginosis, A total of 50 rural women diagnosed as BV randomly categorized into two groups, Group A p...

Background The present study was conducted on the effect of prangos ferulacea vaginal cream on accelerating the recovery of bacterial vaginosis. Methods This randomized controlled clinical trial was conducted on 100 non-pregnant women referring to health centers affiliated to Lorestan University of Medical Sciences in 2016 with the diagnosis of bacterial vaginosis based on the patient's compl...

BACKGROUND Bacterial vaginosis is one of the most prevalent complications among reproductive-aged women. Antibacterial and antifungal effects of Berberis vulgaris have been demonstrated in vitro and in vivo. OBJECTIVES This study aimed to compare the therapeutic effects of the vaginal gel of Berberis vulgaris 5% (in metronidazole base) with metronidazole vaginal gel 0.75% on bacterial vaginos...

BACKGROUND Spontaneous preterm deliveries that occur before the 34th week of gestation, and particularly before the 32nd week of gestation, have been strongly associated to intrauterine infection, ascending from vagina, and represent the largest portion of neonatal deaths and neurological problems. Bacterial vaginosis, characterized by a diminished or absent flora of lactobacilli and increased ...

CONTEXT Vaginal symptoms are one of the most common reasons for gynecological consultation. Clinicians have traditionally diagnosed vaginal candidiasis, bacterial vaginosis, and vaginal trichomoniasis using some combination of physical examination, pH, the wet mount, and the whiff test. OBJECTIVES To evaluate the role of the clinical examination and determine the positive and negative likelih...