نتایج جستجو برای: barrel cortex
تعداد نتایج: 149762 فیلتر نتایج به سال:
Layer IV of rodent somatosensory cortex contains identifiable networks of neurons, called "barrels," that are related one-to-one to individual whiskers on the face. A previous study (Simons and Carvell, 1989) described differences between the response properties of thalamic and cortical vibrissa neurons and proposed that these transformations can be explained by several features of barrel anato...
Single functional column activated by stimulation of C3 vibrissa was visualized in the mouse somatosensory cortex with 2-deo-xyglucose autoradiography. The column was cylindrical in shape and extended through the entire cortical thickness. The darkest labeling was found in layer IV, over the anatomical C3 vibrissal barrel. The functional column stretched horizontally over parts of adjacent barr...
The rodent whisker-barrel system has been an ideal model for studying somatosensory representations in the cortex. However, it remains a challenge to experimentally stimulate whiskers with a given pattern under spatiotemporal precision. Recently the optogenetic manipulation of neuronal activity has made possible the analysis of the neuronal network with precise spatiotemporal resolution. Here w...
To reveal the dynamics of neurophysiological changes in the rat barrel cortex induced by conditioned stimulation we recorded the local micro-electroencephalographic (EEG) activity and evoked potentials (EPs) in barrel cortex to stimulation of a single vibrissa before and after pairing it with a mild electric shock applied to the rat's tail. Following the introduction of the reinforcing stimulus...
The rate at which neurons fire has wide-reaching implications for the coding schemes used by neural systems. Despite the extensive use of the barrel cortex as a model system, relatively few studies have examined the rate of sensory activity in single neurons in freely moving animals. We examined the activity of barrel cortex neurons in behaving animals during sensory cue interaction, during non...
Studies utilizing general learning and memory tasks have suggested the importance of neocortical structural plasticity for memory consolidation. However, these learning tasks typically result in learning of multiple different tasks over several days of training, making it difficult to determine the synaptic time course mediating each learning event. The current study used trace-eyeblink conditi...
Associative memory is essential for cognition, in which associative memory cells and their plasticity presumably play important roles. The mechanism underlying associative memory extinction vs. maintenance remains unclear, which we have studied in a mouse model of cross-modal associative learning. Paired whisker and olfaction stimulations lead to a full establishment of odorant-induced whisker ...
Three days of fear conditioning that combines tactile stimulation of a row of facial vibrissae (conditioned stimulus, CS) with a tail shock (unconditioned stimulus, UCS) expands the representation of "trained" vibrissae, which can be demonstrated by labeling with 2-deoxyglucose in layer IV of the barrel cortex. We have also shown that functional reorganization of the primary somatosensory corte...
A fundamental problem in the study of cortical development is the extent to which the formation and refinement of synaptic circuitry depends upon sensory experience. The barrel cortex is a useful model system to study experience-dependent cortical development because there is a simple mapping of individual whiskers to the corresponding barrel columns in the cortex. We investigated experience-de...
Rats use their facial vibrissae ("whiskers") to locate and identify objects. To learn about the neural coding of contact between whiskers and objects, we investigated the representation of single-vibrissa deflection by populations of cortical neurons. Microelectrode arrays, arranged in a geometric 10 x 10 grid, were inserted into the thalamo-recipient layers of "barrel cortex" (the vibrissal re...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید