BACKGROUND Saccharomyces cerevisiae BY4741 is an auxotrophic commonly used strain. In this work it has been used as host for the expression and secretion of human interleukin-1beta (IL1beta), using the cell wall protein Pir4 as fusion partner. To achieve high cell density and, consequently, high product yield, BY4741 [PIR4-IL1beta] was cultured in an aerated fed-batch reactor, using a defined m...

The aim of this article is to present the Iterative Model Predictive Controller, inmpc, as a good candidate to control chemical batch reactors. The proposed control approach is derived from a model-based predictive control formulation which takes advantage of the repetitive nature of batch processes. The proposed controller combines the good qualities of Model Predictive Control (mpc) with the ...

Sequencing batch reactor (SBR) is one of several periodically operated, suspended-growth activated sludge system. It has an advantage for nitrogen removal which is difficult to remove with conventional system. This paper reviewed the nitrogen removal performance in SBR for several different industrial wastewaters and discussed the factors which may affect the treatment performance. Several modi...

the performance of a plug flow electrocoagulation reactor for the treatment of cattle abattoir(slaughterhouse) wastewater was investigated. a cylindrical iron reactor was operated as a cathode at arecycling batch mode while three iron rods located at the center of the reactor were used as an anode. theeffects of different parameters, including the current density, the supporting electrolyte dos...

This study presents an investigation of electrochemical variables and an application of the optimal parameters in operating a continuous upflow electrocoagulation reactor in removing dye. Direct red 23, which is azo-based, was used as a representative of direct dyes. First, a batch mode was employed to optimize the design parameters: electrode type, electrode distance, current density and elect...

Fermentation of sugar by Saccharomyces cerevisiae, for production of ethanol in an immobilized cell reactor (ICR) was successfully carried out to improve the performance of the fermentation process. The fermentation set-up was comprised of a column packed with beads of immobilized cells. The immobilization of S. cerevisiae was simply performed by the enriched cells cultured media harvested at e...

This article describes the use of biofilm reactors for the production of various chemicals by fermentation and wastewater treatment. Biofilm formation is a natural process where microbial cells attach to the support (adsorbent) or form flocs/aggregates (also called granules) without use of chemicals and form thick layers of cells known as "biofilms." As a result of biofilm formation, cell densi...

The absence of a stable operational state in polymerization reactors that operates in batches is factor that determine the need of a special control system. In this study, advanced control methodology is implemented for controlling the operation of a batch polymerization reactor for polystyrene production utilizing model predictive control. By utilizing a model of the polymerization process, th...

The optimal operation of batch processes has attracted more attention in recent years since, in the face of growing competition, it is a natural choice for reducing production costs, improving product quality, and meeting safety requirements and environmental regulations. Since the models currently available in industry are poor and carry a large amount of uncertainty, standard model-based opti...

This experiment examines two esterification reactions: the de-esterification of ethyl benzoate into benzoic acid and the transesterification of palm oil into biodiesel. Through the de-esterification of ethyl benzoate, we mimicked the processes and experimental designs that are involved in the production of API’s (active pharmaceutical ingredients). The transesterification of palm oil allowed us...