We report measurements of the relative binding affinity of CAP for DNA sequences which have been systematically mutated in the region flanking the consensus binding site. Our experiments focus on the locus one helical turn from the dyad axis where DNA bending toward the minor groove is induced upon C-AP binding. The binding free energy and extent of bending are moderately well correlated for th...

OBJECTIVES The purposes of this study were to evaluate the cantilevered bending strength and failure modes of locking screws inserted at various angles in a plate with fully circumferential threaded holes. As an additional measure, the amount of screw head prominence at these angles was also assessed. METHODS Standard 3.5-mm locking screws were inserted into round fully circumferential thread...

Agricultural waste fibers have been found to be suitable as reinforcement in cement-based composites, but studies on oil palm fiber as reinforcement in gypsum-cement wall panels are scarce. A mixture of two equal weights of gypsum and cement, with water-binder ratios of 0.45 and 0.55 were prepared. In each mix a varying percentage of fiber contents of 2%, 3% and 4% by weight of the binders were...

many researchers have been efforted to identify the shape of distribution of stress and strength of castellated beam and base on that, offer a method for design that members. through this methods, comparing virendil method by simplicity and reasonable results, have been used widly. regardless from shortcoming of this method, there is two idea for distribution of stresses via primary bending in ...