One of the major factors limiting the staging accuracy of conventional magnetic resonance imaging (MRI) for prostatic carcinoma, is the similarity in signal intensity between tumor and coexisting benign prostatic hyperplasia (BPH). As neovascularity is an independent indicator of pathological state, dynamic contrast-enhanced MRI may yield additional information. This study correlates the histop...

Chlormadinone acetate (CMA) and cyproterone acetate have been used in medicaltreatment of human benign prostatic hyperplasia (BPH) or prostatic carcinoma [2,3,8,9]. The atrophic effects of CMA on the prostate of rats and dogs have been previously reported from our laboratory[5,6]. Using spontaneous BPH dogs we found that immunostaining of androgen receptor (AR) in both epithelial and stromal fi...

INTRODUCTION Posterior urethral strictures after prostatic radiotherapy or surgery for benign prostatic hyperplasia (BPH) refractory to minimal invasive procedures (dilation and/or endoscopic urethrotomy) are challenging to treat. Published reports of alternative curative management are extremely rare. This is a preliminary report on the treatment of these difficult strictures by urethroplasty....

BACKGROUND Yukmijihwang-tang, a traditional herbal formula, has been used for treating disorder, diabetic mellitus and neurosis in China (Liu-wei-di-huang-tang in Chinese), Japan (Lokumijio-to in Japanese) and Korea for many years. In this study, we investigated the effects of Yukmijihwang-tang water extract (YJT) on the development of benign prostatic hyperplasia (BPH) using a rat model of tes...

When physician carries out the clinical survey of a patient with benign prostatic hyperplasia (BPH) symptom to reach the initial evaluation/diagnosis of BPH symptom, the existing initial evaluation method of BPH based on the international prostate symptom score (I-PSS) usually use the objective evaluation/diagnosis method with crisp values without considering fuzzy information. However, this no...

Background: Old age, obesity and androgens are more vulnerable to prostatic disorders. Benign Prostatic Hyperplasia (BPH) is a common problem for adults. Objectives: To determine the morphological changes of prostate gland effects Estrogen levels in obese versus non-obese males with BPH. Methods: A cross sectional study was conducted on sixty patients an emergency clinic Dr. Ruth Pfau, Dow univ...

Benign prostatic hyperplasia (BPH) is one of the most common diseases in the senior men and age plays an important role in the initiation and development of BPH. Mammalian cells primarily use the autophagy-lysosome system to degrade misfolded/aggregated proteins and dysfunctional organelles such as mitochondria and suppress pyroptosis, a type of cell death that stimulates inflammatory responses...

BACKGROUND. The incidence of prostate cancer (PCa) and benign prostatic hypertrophy (BPH) continues to rise in the Western world. The development and growth of the prostate gland depends on androgen stimulation. Dihydrotestosterone (DHT) is the primary androgen responsible for prostate development and also for the pathogenesis of benign prostatic hyperplasia (BPH).DHT is synthesized in prostate...

Abstract Introduction There is considerable evidence describing the benefits of a plant-based diet and cardiovascular metabolic disease. Emerging studies have evaluated association between diets urologic conditions affecting men’s health. Objective We performed systematic review literature on potential role may play in following health topics: prostate cancer (PCa), erectile dysfunction (ED), b...

INTRODUCTION AND OBJECTIVES Prostatic inflammation could be a key component in prostate enlargement and benign prostatic hyperplasia (BPH) progression. Our aim was to characterize inflammatory cells infiltrate within BPH tissue and to correlate inflammation and clinical data. MATERIAL AND METHODS Inflammation was profiled on three clinical outcome tissue microarrays (TMAs), including 282 pati...