benzothiazoles

نتایج جستجو برای: benzothiazoles

تعداد نتایج: 209 فیلتر نتایج به سال:

Novel benzothiazole containing 4H-pyrimido[2,1-b]benzothiazoles derivatives: One pot, solvent-free microwave assisted synthesis and their biological evaluation

Journal: :Arabian Journal of Chemistry 2019

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Synthesis of rhodium(III) complexes with tris/tetrakis-benzimidazoles and benzothiazoles-quick identification of cyclometallation by nuclear magnetic resonance spectroscopy

Journal: :Magnetic Resonance in Chemistry 2009

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Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay.

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2002

Volker Heiser Sabine Engemann Wolfgang Bröcker Ilona Dunkel Annett Boeddrich Stephanie Waelter Eddi Nordhoff Rudi Lurz Nancy Schugardt Susanne Rautenberg Christian Herhaus Gerhard Barnickel Henning Böttcher Hans Lehrach Erich E Wanker

Preventing the formation of insoluble polyglutamine containing protein aggregates in neurons may represent an attractive therapeutic strategy to ameliorate Huntington's disease (HD). Therefore, the ability to screen for small molecules that suppress the self-assembly of huntingtin would have potential clinical and significant research applications. We have developed an automated filter retardat...

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