نتایج جستجو برای: betulinic acid
تعداد نتایج: 747458 فیلتر نتایج به سال:
BACKGROUND & AIMS In cholestatic syndromes, body accumulation of bile acids is thought to cause itching. However, the mechanisms supporting this effect remain elusive. Recently, GPBAR1 (TGR5) a G-protein coupled receptor has been shown to mediate itching caused by intradermal administration of DCA and LCA. 6α-ethyl-3α, 7α-dihydroxy-24-nor-5β-cholan-23-ol (BAR502) is a non-bile acid dual ligand ...
We herein report on the synthesis of a pentacyclic triterpene functionalized through derivation betulinic acid with hydroxybenzotriazole. The compound was fully characterized by proton (1H-NMR), carbon-13 (13C-NMR), heteronuclear single quantum coherence (HSQC) and distortionless enhancement polarization transfer (DEPT-135 DEPT-90) nuclear magnetic resonance. Ultraviolet (UV), Fourier-transform...
We consider spectral radius algebras associated to C0 contractions. When the operator A is algebraic, we describe all invariant subspaces that are common for operators in its spectral radius algebra BA. In all other situations BA is weakly dense and we characterize a set of rank one operators in BA that is weakly dense in L(H).
Three isoflavanoids, isovestitol (1), medicarpin (2), and sativan (3), along with another known compound, betulinic acid (4), were isolated from the root of Sesbania grandiflora. The structures of the isolated compounds were characterised by means of spectroscopic techniques (UV, IR, MS, 1H- and 13C-NMR, DEPT, COSY, HMQC, HMBC, and MS analysis). All the tested compounds 1-4 exhibited antituberc...
Mauritia flexuosa L. f., Arecaceae, is an endemic species of South America. This species was studied with the intent to isolate the constituents of its roots. After the fractionation of the n-hexane and methanolic extracts from the roots of M. flexuosa, six triterpenes were obtained: friedelin, taraxerone, lupenyl acetate, lupenone, betulin and betulinic acid, along with three flavonoids: rutin...
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