نتایج جستجو برای: bfc
تعداد نتایج: 193 فیلتر نتایج به سال:
The activity of cytochrome P450 enzymes depends on the enzyme NADPH P450 oxidoreductase (POR). The aim of this study was to investigate the activity of the equine CYP3A94 using a system that allows to regulate the POR protein levels in mammalian cells. CYP3A94 and the equine POR were heterologously expressed in V79 cells. In the system used, the POR protein regulation is based on a destabilizin...
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dendrobium chrysanthum (orchidaceae) is highly valued in the ornamental industry and has important medicinal properties used in the preparation of herbal medicines in different parts of the world. however, this orchid species is getting depleted from its natural habitats due to unsystematic collections. therefore, in the present study, an efficient mass propagation protocol through direct shoot...
مقدمه: فراخوان نوزادان با آزمونهای اولیه غیرطبیعی در غربالگری کمکاری مادرزادی تیروئید، اولین گام در شناسایی و درمان نوزادان هیپوتیروئید است. با توجه به اهمیت میزان فراخوان در ارزیابی هزینه ـ سود و قابل اجرا بودن برنامه غربالگری کمکاری مادرزادی تیروئید، پیشبینی میزان فراخوان میتواند نقش بسزایی در بهینهسازی تخصیص نیروها و جلوگیری از اتلاف آن ایفا نماید. این مقاله شامل بررسی روند سری زمانی م...
Parental consanguinity: a probable cause for the high incidence of permanent neonatal hypothyroidism
Introduction: To assess the relationship between parental consanguinity and permanent congenital hypothyroidism (PCH). Materials And Methods: From February 1998 to August 2002, cord dried blood spot samples, viz. only live births, in eight hospitals and a rural birth center in Tehran and Damavand were collected on Whatman BFC 180 filter papers. Samples with cord TSH 20 mU/L (two-site IRMA) ...
Among Neotropical cracids (Galliformes), many taxa are declining rapidly in population size and facing local extinction. However, the Brazilian Pantanal, several species occur sympatrically abundant numbers to allow for long-term studies. Therefore, study was intended collect data statistically evaluate life history patterns of Bare-faced Curassow (Crax fasciolata), a high-conservation-priority...
Azamulin [14-O-(5-(2-amino-1,3,4-triazolyl)thioacetyl)-dihydromutilin] is an azole derivative of the pleuromutilin class of antiinfectives. We tested the inhibition potency of azamulin toward 18 cytochromes P450 using human liver microsomes or microsomes from insect cells expressing single isoforms. In a competitive inhibition model, IC50 values for CYP3A (0.03–0.24 M) were at least 100-fold lo...
17 -Ethynylestradiol (EE) inactivates cytochrome P450 3A5 (3A5) in the reconstituted system in a mechanism-based manner. The inactivation is dependent on NADPH, and it is irreversible. The inactivation of 3A5 by EE is also dependent on cytochrome b5 (b5). The values for the KI and kinact of the 7-benzyloxy-4-(trifluoromethyl)coumarin O-debenzylation activity of 3A5 are 26 M and 0.06 min , respe...
در سالیان اخیر هزینه های بالای انرژی و مواد باعث شده است که کوشش های بسیاری برای رسیدن به راندمان بالاتر برای مبدل های حرارتی جهت کوچکتر شدن ابعاد، بهینه سازی مصرف انرژی و در نهایت کاهش هزینه ها صورت گیرد. افزایش راندمان مبدل حرارتی به معنی حداکثر افزایش انتقال حرارت به همراه حداقل افزایش افت فشار است. از جمله روش های غیرفعال افزایش انتقال حرارت در مبدل های حرارتی، استفاده از ملحقات است. در این...
The purpose of this work was to develop a practical scale-up model for a solvent-based pan-coating process. scale up of adsorption column Practical scale-up rules to determine. ABSTRACT: Although significant progress had been made in developing general scale-up rules for an aqueous pan-coating process, there. Practical scale-up rules to determine the key parameters pan load, pan speed, spray ra...
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