OBJECTIVE To investigate the safety and efficacy of percutaneous endoscopic gastrostomy/jejunostomy (PEG/PEJ) combined with percutaneous transhepatic biliary drainage (PTCD) in treating malignant biliary obstruction. SUBJECTS AND METHODS Nine patients (6 males and 3 females, average age 71.3 ± 5.5 years) with complete obstruction of the biliary tract were treated with PEG/PEJ after PTCD. The ...

Paraneoplastic syndrome associated with prostate cancer is extremely rare. We report a patient who presented with cholestatic jaundice without biliary duct obstruction, hepatic involvement, or infection. After a few detailed examinations, prostate cancer was diagnosed. After treatment with bicalutamide and leuprolide, the patient's symptoms and laboratory abnormalities were reversed. Cholestati...

biliary atresia is characterized by the progressive obliteration of extra- and intrahepatic biliary duct system leading to the obstruction of bile flow in infancy. the cause(s) of biliary atresia remain unclear and many surgical options for bypassing the atretic segment have been described. 1-3 biliary atresia may be associated with small bowel atresia.  the surgical interventions for biliary d...

BACKGROUND Eosinophilic cholangitis (EC) is a rare benign disorder of the biliary tract which can cause biliary obstruction. Similar to other disease processes involving the bile ducts, this disorder can pose a difficult diagnostic challenge as it can mimic cholangiocarcinoma. METHODS A systematic search of the scientific literature was carried out using PubMed to access all publications rela...

In patients with inoperable hilar cholangiocarcinoma (HCCA), palliative endoscopic or percutaneous drainage provides benefits in terms of symptomatic improvement and quality of life. Endoscopic biliary stent placement is considered the gold standard, with metal stents preferred over plastic stents in patients with more than three months of life expectancy. However, the endoscopic management of ...

Obstructive jaundice is a common surgical problem that occurs when there is blockage of the passage of conjugated bilirubin from liver to intestine. In most benign biliary diseases, jaundice is intermittent and incomplete. Only a few diseases (e.g. primary sclerosing cholangitis) result in persistent obstructive jaundice, or even in biliary cirrhosis and portal hypertension, and most cases are ...

Annular pancreas (AP) is a rare congenital abnormality in which the ventral portion of fails to rotate with duodenum during embryological development, thus causing remain partially or fully enveloped around duodenum. The actual incidence AP unknown, as many cases are asymptomatic and undiagnosed. Adults may present variety symptoms suggestive gastric outlet obstruction, gastrointestinal bleedin...

BACKGROUND Ectopic biliary drainage is a rare congenital anomaly on which we have scarce data in the current literature. METHODS The data were collected from the records of 400 endoscopic retrograde cholangio-pancreatography (ERCP). In this report, we present 10 cases (male/female: 9/1, mean age 54 years, range 38-74) with ectopic biliary openings into the duodenum and/or stomach diagnosed by...

AIM To assess the feasibility and effectiveness of a novel application of percutaneous intraductal radiofrequency (RF) for the treatment of biliary stent obstruction. METHODS We specifically report a retrospective study presenting the results of percutaneous intraductal RF in patients with biliary stent occlusion. A total of 43 cases involving biliary stent obstruction were treated by placing...

Twenty patients with chronic pancreatitis and signs of biliary obstruction were treated by endoscopic placement of self expandable metal mesh stents, and followed up prospectively. Eleven had been treated previously with plastic endoprostheses. All had persistent cholestasis, seven patients had jaundice, and three overt cholangitis. Endoscopic stent placement was successful in all cases. No ear...