The increasing need for more efficient synthetic methods and sustainable processes can be seen as a major driving force for new inventions; it also stimulates the creative rethinking of known concepts, which, in turn, will lead to the development of innovative chemistry. For example, starting from the challenge to mimic and understand enzymatic transformations, organocatalysis has now become an...

Determining kinetics of molecular binding reactions is important for characterizing biological processes and for predicting behavior of detection strategies that involve binding. We used the T-sensor and a numerical model to determine kinetic parameters (equilibrium binding and rate constants) of a bimolecular binding reaction between the fluorescent probe prodan and human serum albumin ()-ISA)...

Transition state theory (TST) 1 is the most widely used theory for calculating rates of bimolecular eactions occurring in the gas phase and in condensed phases. TST is also incorporated into the widely used RRKM theory for unimolecular reactions. The popularity of TST is largely due to its simplicity and its usefulness for correlating trends in reaction rates in terms of easily interpreted quan...

The effect of three aromatic amines namely aniline (AN), dimethyl aniline (DMAN) and diethyl aniline (DEAN) on emission properties of a coumarin derivative 6-methyl-3azidoacetyl coumarin (6M3AAC) in acetonitrile was studied by means of steady state fluorescence spectroscopy. The quenching of fluorescence intensity was observed in the presence of amines. The quenching process was characterized b...

In the present work basic aspects of the bimolecular electron transfer processes have been studied by photochemical means and the heterogeneous electrochemical electron transfer processes have been applied in corrosion research and electroanalysis. Photoinduced electron transfer (ET) reactions were studied from the fluorescence quenching experiments using coumarins and quinones as the fluoropho...

Considerable effort has been directed recently toward measuring rate parameters for intramolecular redox reactions, typically involving electron transfer between a pair of transition metals linked by an organic bridge.lW3 Such reactions offer important advantages over bimolecular processes for investigating detailed aspects of electron transfer, since the uncertainties concerning the energetics...

The chemical reactivity of atomic boron, B(Pj), with inorganic and organic molecules is a fascinating subject of research from the experimental1-35 and theoretical viewpoints.29,30,36-46 Atomic boron resides in the same row as carbon, nitrogen, and oxygen.47 Although the reaction dynamics and kinetics of the latter elements (C, N, O) have been studied in depth,48-53 an investigation of elementa...

Numerous biological processes involve association of a protein with its binding partner, an event that is preceded by a diffusion-mediated search bringing the two partners together. Often hindered by crowding in biologically relevant environments, three-dimensional diffusion can be slow and result in long bimolecular association times. Similarly, the initial association step between two binding...