The present investigation describes the influence of the concentration of PEG 6000 as a melt binder and ratio of HPMC K4M : PVP on Zolpidem tartrate controlled-release tablet formulations using 3(2) full factorial design. The ratio of HPMC K4M and PVP K30 (X(1)) and the concentration of melt binder (X(2)) were selected as independent variables, and drug release at 1 hr (Q(1)), 4 hr (Q(4)), 8 hr...

Mortars with mud, gypsum and lime as binder have, since ancient times, been used for very different applications. The characterisation of these historic mortars was until 1970–1980 mostly based on traditional wet chemical analyses but the interpretation of these results is difficult and often impossible without a good knowledge of the nature of the different mortar components. More recently dev...

It is recognized that mycotoxins can cause a variety of adverse health effects in animals, including altered gastrointestinal barrier function. It is the aim of the present study to determine whether mycotoxin-contaminated diets can alter the oral bioavailability of the antibiotics doxycycline and paromomycin in pigs, and whether a mycotoxin adsorbing agent included into diets interacts with th...

In this paper, a wax-based binder was developed for low-pressure injection molding of very fine (0,4 μm) average particle size alumina ceramic bodies. The major component used in the binder mixture was paraffin wax. The process of binder removal from the green ceramics presented several difficulties especially when the ceramic powder was very fine, and the pieces had large cross-section. The pr...

Absorption of cobalamin free or bound to chicken serum was assessed in nine patients with pancreatic insufficiency. Simultaneously the in vitro effect of duodenal juice collected from six patients and seven controls was tested on labelled cobalamin complexed to chicken serum or to R salivary binder. Malabsorption of free cobalamin was observed in one of nine patients and in four of nine patient...

• Water penetration in concrete with different cracks is evaluated by chloride penetration. The evaluation of self-healing through presents reliable results. UHPFRC shows better than conventional and high-performance concretes. This study a novel methodology to evaluate the capability Ultra High-Performance Fiber-Reinforced Concrete (UHPFRC) designed compare types. procedure used combines loadi...

The development of alternative anode materials out of flexible composite nanofibers has seen a growing interest. In this paper, binary carbon nanofiber electrodes of SnO2/NiO and Sn nanoparticles are produced using a scalable technique, Forcespinning (FS), and subsequent thermal treatment (carbonization). The Sn/C composite nanofibers were porous and flexible, while the SnO2/NiO composite nanof...

The aim of this study is to investigate the possibility of a freeform fabrication of porous ceramic parts through selective laser sintering (SLS). SLS was proposed to manufacture ceramic green parts because this additive manufacturing technique can be used to fabricate three-dimensional objects directly without a mold, and the technique has the capability of generating porous ceramics with cont...

Monolithic ceramics have been fabricated from coated green fibers to create fibrous microstructures. The fibrous monoliths consist of high aspect ratio polycrystalline regions (cells) of a primary phase separated by thin secondphase regions (cell boundaries) designed to improve fracture resistance. The cells are the remnants of the green fiber which consists of ceramic powder and a polymer bind...

In the technologically advanced era that we currently live in, there is a growing demand for cheaper and more durable materials for a variety of purposes. The most important safety feature of an automobile is its braking system. The ability of brakes is to provide safe and repeatable stopping, which is related to safety of automobiles and human. Automotive friction materials are multi component...