This study is an attempt to correlate adrenocortical hormonal activity with various cell fractions obtained by homogenization and differential centrifugation of bovine adrenocortical tissue. Bioassays involving the decrease in circulating eosinophils and sodium retention were employed for the estimation of the glucocorticoids and mineralocorticoids respectively. The supernatant was the most act...

We examined the efficacy of termiticidal baits comprised of powdered acellulose and a mineral insecticide, cryolite crystals, in laboratory bioassays against pseudergates ofEastern subterranean termites [Reticulitemzesjavipes (Kollar)]. The influence of cryolite crystal size [0 (control), 0.2, and 20 pm diameter particles] on the overall mortality of termites consuming the bait was determined i...

An approach to the evaluation of carcinogenic risk resulting from exposure to a given chemical is presented in place of a reliance on two-year rodent bioassays. An emphasis is placed on evaluation of the potential DNA reactivity or increased cell proliferation that can be produced by a chemical. The special cases of immunosuppressive and estrogenic chemicals are considered. These evaluations ar...