نتایج جستجو برای: biofunctionalization

تعداد نتایج: 250  

2011
Petra Birgit Welzel Silvana Prokoph Stefan Zschoche Uwe Freudenberg

Heparin and four-armed, end-functionalized polyethylene glycol (starPEG) were recently combined in sets of covalently linked biohybrid hydrogel networks capable of directing various therapeutically relevant cell types. To extend the variability and applicability of this novel biomaterials platform, the influence of size and molar ratio of the two building blocks on the hydrogel properties was i...

2017
Xuefeng Wang Zhong Mei Yanyan Wang Liang Tang

Introducing sulfhydryl groups to biomolecules to functionalize gold nanorods (GNRs) is an attractive method that involves the creation of a strong Au-S bond. Previously, we developed a facile method to functionalize GNR surfaces by thiolating antibodies using Traut's reagent. In the current study, we evaluated several methods for the introduction of thiol groups onto the surface of GNRs by usin...

Journal: :Journal of biomedical materials research. Part B, Applied biomaterials 2016
Pablo Sevilla Kyle V Vining Javier Dotor Daniel Rodriguez F Javier Gil Conrado Aparicio

TGF-β1 is the most related cytokine with the production of fibrotic tissue. It plays an important role on the production of collagen by fibroblasts and other types of cells. The inhibition of this cytokine reduces fibrosis in various types of tissue. Biofunctionalization of dental and orthopedic implants with biomolecules enables modification of the physical, chemical and biochemical properties...

2010
D. Regatos D. Fariña A. Calle A. Cebollada B. Sepúlveda G. Armelles L. M. Lechuga

In this paper, we analyze the magnetoplasmonic MP features and sensing capabilities of Au/Fe/Au trilayer structures, as transducers of the magneto-optic surface plasmon resonance MOSPR biosensor. This biosensor, which can surpass the sensitivity of the standard SPR sensor, is based on a MP modulation technique generated by the simultaneous stimulation of the surface plasmon polaritons SPP and t...

Journal: :Journal of the Royal Society, Interface 2015
Marwa Tallawi Elisabetta Rosellini Niccoletta Barbani Maria Grazia Cascone Ranjana Rai Guillaume Saint-Pierre Aldo R Boccaccini

The development of biomaterials for cardiac tissue engineering (CTE) is challenging, primarily owing to the requirement of achieving a surface with favourable characteristics that enhances cell attachment and maturation. The biomaterial surface plays a crucial role as it forms the interface between the scaffold (or cardiac patch) and the cells. In the field of CTE, synthetic polymers (polyglyce...

2018
Matěj Horáček Rachel E Armstrong Peter Zijlstra

The functionalization of gold nanoparticles with DNA has been studied extensively in solution; however, these ensemble measurements do not reveal particle-to-particle differences. Here we study the functionalization of gold nanorods with thiolated single-stranded DNA (ssDNA) at the single-particle level. We exploit the sensitivity of the plasmon resonance to the local refractive index to study ...

2014
Nalinikanth Kotagiri Jin-Woo Kim

Carbon nanotubes (CNTs) have recently been in the limelight for their potential role in disease diagnostics and therapeutics, as well as in tissue engineering. Before these medical applications can be realized, there is a need to address issues like opsonization, phagocytosis by macrophages, and sequestration to the liver and spleen for eventual elimination from the body; along with equally imp...

2014
Sen Jia Xinjie Yang Wen Song Lei Wang Kaixiu Fang Zhiqiang Hu Zihui Yang Chun Shan Delin Lei Bin Lu

Engineered bone substitutes are being extensively explored in response to growing demand. However, the angiogenesis that occurs during bone formation is often overlooked in scaffold design. In this novel study, we incorporated two small interfering RNAs (siRNAs), ie, small interfering RNA targets casein kinase 2 interaction protein 1 (siCkip-1) and small interfering RNA targets soluble VEGF rec...

2013
Wenjie Zhang Zihui Li Qingfeng Huang Ling Xu Jinhua Li Yuqin Jin Guifang Wang Xuanyong Liu Xinquan Jiang

BACKGROUND AND METHODS Various methods have been used to modify titanium implant surfaces with the aim of achieving better osseointegration. In this study, we fabricated a clustered nanorod structure on an acid-etched, microstructured titanium plate surface using hydrogen peroxide. We also evaluated biofunctionalization of the hybrid micro/nanorod topography on rat bone marrow mesenchymal stem ...

2016
Birgit Huber Sascha Engelhardt Wolfdietrich Meyer Hartmut Krüger Annika Wenz Veronika Schönhaar Günter E. M. Tovar Petra J. Kluger Kirsten Borchers

Blood vessel reconstruction is still an elusive goal for the development of in vitro models as well as artificial vascular grafts. In this study, we used a novel photo-curable cytocompatible polyacrylate material (PA) for freeform generation of synthetic vessels. We applied stereolithography for the fabrication of arbitrary 3D tubular structures with total dimensions in the centimeter range, 30...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید