One criterion recommended (1,2) for establishing the maximal allowable imprecision is derived from the biological variability data. According to this criterion, the metrological coefficient of variation must be equal to or less than one-half of the within-subject biological coefficient of variation. When information about biological variability is not available, or when current procedures give ...

A model for nutrient uptake rate (V) in phytoplankton is derived: V = n A v S / ( l + h A v S ) where n is cellular number of uptake sites, A is area of the uptake site, h is time required for handling one nutrient ion, vis the mass transfer coefficient, and S i s substrate concentration. The model is based on 2 time requirements necessary for active uptake of nutrients: (i) time required for r...

The pharmacokinetics of amikacin sulfate was investigated following a single intramuscular (i.m.) or subcutaneous (s.c.) administration (10 mg/kg). The plasma concentration versus time data were analysed using the biexponential equation for first-order absorption and elimination phases for both the i.m. and s.c. routes. The absorption half life values for the i.m. and s.c. routes were found to ...