Treatment of thiol ester with bis(iodozincio)alkane in the presence of palladium catalyst followed by silylation affords Z-silyl enol ether chemo-, regio- and stereoselectively.

Given the opposing responses reported for bisphenol A (BPA) in terms of induction obesogenic effects and impaired lipid metabolism, increasing use F (BPF), relatively low information available regarding bis(3-chloro-2- hydroxypropyl) ether (BADGE·2HCl) aquatic organisms, this work aims to zebrafish liver cell line (ZFL) as an alternative model characterize toxicity metabolism disruptive potenti...

In the title compound, {[Mn(NCS)(2)(C(10)H(8)N(2))(2)]·2C(4)H(10)O}(n), the Mn(II) ion is coordinated by four N-bonded 4,4'-bipyridine (bipy) ligands and two N-bonded thio-cyanate anions in a distorted octa-hedral coordination geometry. The asymmetric unit consists of one Mn(II) ion and two bipy ligands each located on a twofold rotation axis, as well as one thio-cyanate anion and one diethyl e...

The synthesis of methyl 3,3-bis[4-(dimethylamino)phenyl]-2,2-dimethylpropanoate is achieved by means the alkylation isobutyrate silyl enol ether with bis[4-(dimethylamino)phenyl]methanol, facilitated using 1,1,1,3,3,3-hexafluoroisopropanol (HFIP) as a solvent and reaction promoter. proceeds smoothly to produce mentioned compound in good yield via metal additive-free procedure. corresponding est...

Increasing evidence of lipid peroxidation in food deterioration and pathophysiology of diseases have revealed the need for a pure lipid hydroperoxide (LOOH) reference as an authentic standard for quantification and as a compound for biological studies in this field. Generally, LOOH is prepared from photo- or enzymatically oxidized lipids; however, separating LOOH from other oxidation products a...

We analyzed the degradation features by measuring capacitance–voltage characteristics after electrically aging blue thermally activated delayed fluorescence (TADF) organic light-emitting diodes (OLEDs). The measurement was investigated in terms of hole transfer layer (HTL) and electron (ETL) structures. For HTL, three different materials—N,N′–bis(naphthalen–1–yl)–N,N′–bis(phenyl)–benzidine (NPB...

Jamieson, Daniel P. Ph.D., Purdue University, December 2013. Continued Progress Towards Efficient Syntheses of Cephalostatin North 1 Analogs. Major Professor: Philip L. Fuchs. The cephalostatins and ritterazines represent an intriguing class of marine natural products in both structure and biological activity, and the progress towards the synthesis of high valued analogs with a focus on process...

Endocannabinoids have been implicated in cancer. Increasing endogenous 2-arachidonoylglycerol (2-AG) by blocking its metabolism inhibits invasion of androgen-independent prostate cancer (PC-3 and DU-145) cells. Noladin ether (a stable 2-AG analog) and exogenous CB1 receptor agonists possess similar effects. Conversely, reducing endogenous 2-AG by inhibiting its synthesis or blocking its binding...

The title compound [Mn(6)(C(7)H(4)NO(3))(5)(CH(3)CO(2))(2)(C(5)H(8)N(2))(4)(C(3)H(7)NO)(2)]·(C(2)H(5))(2)O·C(3)H(7)NO·CH(3)OH·0.12H(2)O, abbreviated as Mn(II)(OAc)(2)[15-MC(MnIII(N)shi)-5](EtIm)4(DMF)2·diethyl ether·DMF·MeOH·0.12H(2)O (where (-)OAc is acetate, MC is metallacrown, shi(3-) is salicylhydroximate, EtIM is n-ethylimidazole, DMF is N,N-dimethylformamide, and MeOH is methanol) contain...