Rat-bite fever (RBF) is a zoonotic infection caused by Gram-negative microaerophilic Streptobacillus moniliformis and Spirillum minus. Rat-bite fever predominantly affects the population in areas of poor socioeconomic status. The disease has been reported in high-income countries where rats are commonly kept as pets. The case described below is that of an 8-month-old infant boy who was diagnose...

Background. Due to their ability recruit immune cells kill tumor directly, bispecific T cell engager antibodies (BiTE) hold great potential in redirecting therapies. BiTE is able activate through CD3 and target them tumor-expressed antigens. However, there are many components the microenvironment (TME) such as mesenchymal stem (MSCs) that may interfere with function. Herein, we designed an anti...

Abstract Bispecific T cell engager (BiTE) is one of the most promising therapeutic approaches for treatment various malignancies. Humanized mice engrafted with human peripheral blood mononuclear cells (PBMCs) have currently become preclinical platform evaluating effectiveness cancer immunotherapies including BiTE. However, wide application this humanized animal model limited by a strong xenorea...

background: animal bites considered as one of the issues and problems of public health that potentially has the risk of rabies disease. this study was conducted to determine the epidemiology of animal bite in aq qala city during the years1998-2009. methods: in this descriptive cross-sectional study, 13142 cases of animal bite recorded in aq qala city rabies treatment center selected by census m...

this study was done to determine whether high or low dose of anti-snake venom (asv) is better in coagulopathy in victims of envenoming by vipers. this retrospective study was conducted on the 154 patients (mean age ± sd, range) of viper snake bites who were referred to the emergency ward of razi hospital, ahvaz, iran over 2 years period (2004 - 2006). according to the treatment dosage the patie...

The objective of this study was to investigate changes in foraging behavior, hunger-related hormones, and metabolites of dairy cows in response to short-term variations in rumen fill (RF). The effect of RF on intake rate, jaw movements, bite rate and dimensions, and concentrations of plasma ghrelin, and serum insulin and glucose were measured in 4 rumen-cannulated lactating dairy cows (612 +/- ...

BACKGROUND Crocodilians have dominated predatory niches at the water-land interface for over 85 million years. Like their ancestors, living species show substantial variation in their jaw proportions, dental form and body size. These differences are often assumed to reflect anatomical specialization related to feeding and niche occupation, but quantified data are scant. How these factors relate...

Ultrasonography has been used to determine the association between muscle thickness, temporomandibular dysfuntion (TMD), facial morphology, and bite force. The aim of this study was to evaluate signs and symptoms (SS) of TMD using the craniomandibular index (CMI), masseter and anterior temporalis thickness, facial dimensions, and bite force in adolescents (12-18 years of age): 20 (10 males and ...