D a t a s o u r c e s Published and unpublished studies were identified by searching MEDLINE and the Cochrane Controlled Trials Register (last searched August 2001) with combinations and various forms of the terms somatostatin, octreotide, variceal, varices, bleed, hemorrhage, esophag, hematemesis, and melena; reviewing abstracts of conference proceedings and bibliographies of relevant studies;...

Introduction Postmenopausal bleeding (PMB) is the most common symptom of the endometrium. Cervical cancer must also not be forgotten, especially in women with a thin endometrium. Therefore, all women presenting with PMB should undergo evaluation with transvaginal ultrasound to estimate the risk of endometrial cancer, and speculum examination/cervical cytology to rule out cervical pathology. Man...

Direct-acting oral anticoagulants include dabigatran, which is a thrombin inhibitor, and rivaroxaban, apixaban, edoxaban, are anti-Xa agents. These administered in the secondary prophylaxis treatment of venous thromboembolism (VTE) pulmonary embolism (PE), VTE that may develop after major elective orthopedic surgery, reducing stroke systemic occur non-valvular atrial fibrillation, whereas its u...

OBJECTIVES Corticosteroids are frequently used in a range of otorhinolaryngologic conditions due to their anti-inflammatory and antiedematous properties. In this meta-analysis, we aimed to assess the role of preoperative steroids for attenuating intraoperative bleeding during endoscopic sinus surgery among patients with nasal polyps. DATA SOURCES PubMed, SCOPUS, EMBASE, the Web of Science, an...

Post menopausal bleeding is one of the most common conditions referred to gynaecology departments. Up to 5% of these women are found to have malignant, or pre-malignant lesions, with early detection and investigation being crucial for curative treatment. We report on the case of a 73-year-old women referred for having regular menses since 14 years of age and discuss the current investigation an...