Inferior dental anaesthesia via the direct intraoral approach, mandibular conduction anaesthesia via extraoral landmarks(Gow-Gates) and mandibular conduction anaesthesia via the tuberosity approach( Akinosi) were evaluated using pain during injection, aspiration test, pinprick, depth and frequency of anaesthesia, onset and duration of anaesthesia. 120 patients of both sexes, aged from 16 years ...

Sir,—Elliott, Voyvodic and Brownridge recently reported an unexpected subarachnoid block in a parturient, despite careful aspiration testing and prior administration of local anaesthetic via a catheter, presumably located in the lumbar extradural space. 1 We recently described five similar cases of high spinal block produced by the initial test dose alone after negative aspiration testing. 2 We...

BACKGROUND Conventional anesthetic nerve block injections into the mandibular foramen risk causing nerve damage. This study aimed to compare the efficacy and safety of the anterior technique (AT) of inferior alveolar nerve block using felypressin-propitocaine with a conventional nerve block technique (CT) using epinephrine and lidocaine for anesthesia via the mandibular foramen. METHODS Forty...

To the Editor: We report the unintentional administration of 400 mg ropivacaine during an interscalenic block in a patient suffering from hemolytic-uremic syndrome and epilepsy. The patient was scheduled for the creation of an arterio-venous fistula of the left forearm. The interscalenic block was performed with a neurostimulator and 400 mg ropivacaine (6.15 mg·kg–1), instead of the intended 20...

Anesthesia may be considered in terms of two categories: general and regional. The aim of general anesthesia is to induce analgesia, sedation, amnesia, suppression of autonomic reflexes, and relaxation of muscles. Regional anesthesia is more site-specific and is typically divided into three categories based on the location of injection: 1. a central neuraxial block is an injection of an anesthe...

The purposes of the present study were to determine if the direction of the needle orifice during injection of anesthetic into the subarachnoid space, using a 25-gauge Whitacre spinal needle (Becton Dickinson, Franklin Lakes, NJ) to deliver 15 mg of 0.75% hyperbaric bupivacaine, affected the level of sensory blockade achieved, and if there was a difference in time from injection to surgical ane...

BACKGROUND Dexamethasone has been studied as an effective adjuvant to prolong the analgesia duration of local anesthetics in peripheral nerve block. However, the route of action for dexamethasone and its potential neurotoxicity are still unclear. METHODS A mouse sciatic nerve block model was used. The sciatic nerve was injected with 60ul of combinations of various medications, including dexam...

PURPOSE To report the use of intracameral tissue plasminogen activator to dissolve fibrinous membranes and break posterior synechiae in patients with acute HLA-B27-positive iridocyclitis with impending pupillary block. METHODS Two patients with severe acute fibrinous iridocyclitis and seclusio pupillae were identified. Because of the concern of impending pupillary block, intracameral tissue p...

The degeneration-regeneration process induced by bupivacaine injection has been studied in rat extensor digitorum longus (EDL) muscle in the presence or absence of nerve, the presence of tetrodotoxin (TTX)-induced block of nerve impulse conduction, and the presence of vinblastine-induced block of nerve axoplasmic flow associated to TTX block. Seven and 14 days after bupivacaine injection, myosi...