نتایج جستجو برای: blood lipoproteins

تعداد نتایج: 714085  

Journal: :Circulation research 1958
H ENGELBERG

The extent of triglyeeride lipolysis by postheparin lipemia clearing factor (lipoprotein lipase) was studied in vitro in 8 atherosclerotic individuals. Varying doses of heparin were injected intravenously and subcutaneously and blood was drawn at stated time intervals for analysis. The rate of splitting of human low density lipoproteins was then determined by measurement of the rate of release ...

2008

Overview: Lipoproteins are spherical particles that carry lipids, particularly cholesterol and triglyceride, in the plasma. There is a well-established association between dyslipidemias, or disorders of lipoprotein metabolism, and coronary heart disease (CHD): elevated levels of blood cholesterol, especially low-density lipoprotein cholesterol (LDL-C), and low levels of high-density lipoprotein...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2013
Yao Wang Manabu Niimi Kazutoshi Nishijima Ahmed Bilal Waqar Ying Yu Tomonari Koike Shuji Kitajima Enqi Liu Tomohiro Inoue Masayuki Kohashi Yuka Keyamura Tomohiro Yoshikawa Jifeng Zhang Loretta Ma Xiaohui Zha Teruo Watanabe Yujiro Asada Y Eugene Chen Jianglin Fan

OBJECTIVE Apolipoprotein (apo) A-II is the second major apo of high-density lipoproteins, yet its pathophysiological roles in the development of atherosclerosis remain unknown. We aimed to examine whether apo A-II plays any role in atherogenesis and, if so, to elucidate the mechanism involved. METHODS AND RESULTS We compared the susceptibility of human apo A-II transgenic (Tg) rabbits to chol...

2016
Ciaran Skerry Lee G. Klinkenberg Kathleen R. Page Petros C. Karakousis Pere-Joan Cardona

Co-infection with Mycobacterium tuberculosis accelerates progression from HIV to AIDS. Our previous studies showed that M. tuberculosis complex, unlike M. smegmatis, enhances TLR2-dependent susceptibility of CD4+ T cells to HIV. The M. tuberculosis complex produces multiple TLR2-stimulating lipoproteins, which are absent in M. smegmatis. M. tuberculosis production of mature lipoproteins and TLR...

2014
SAILAJA RAO G KRISHNA

Diabetes mellitus is one of the widespread and severe metabolic disorders in human all over the world. The present study was designed to evaluate the potential antihyperlipidemic efficacy of chloroform and ethylacetate extracts ofMomordica dioica seeds in diabetic rats. Diabetes was induced by giving Streptozotocin intraperitoneally, rats which showed blood glucose levels of >250 mg/dlwere sele...

Journal: :The Biochemical journal 1960
J E LOVELOCK A T JAMES C E ROWE

In Part 1 (James, Lovelock & Webb, 1959) and in the earlier work of Altman, Watman & Solomon (1952), it was reported that the cellular constituents of the blood are able to incorporate activity from sodium [Me-14C]acetate into their lipid components. It was also shown that the radioactive lipids synthesized by the cells are transferred during the course of incubation in vitro to the plasma lipo...

Journal: :Journal of lipid research 1977
A Pagnan R J Havel J P Kane L Kotite

Two discrete populations of very low density lipoproteins, with fast and slow pre-beta electrophoretic mobility, were found in 50% of normolipemic and 30% of hyperlipemic individuals selected at random. The two populations were isolated by preparative electrophoresis from five hyperlipemic subjects. The particles comprising the slow component were smaller than those of the fast component and th...

Journal: :American journal of physiology. Endocrinology and metabolism 2012
Nicholas P Greene James D Fluckey Brad S Lambert Elizabeth S Greene Steven E Riechman Stephen F Crouse

PPARδ is a transcription factor regulating the expression of genes involved in oxidative metabolism, which may regulate blood cholesterols through transcription of oxidative and lipoprotein metabolism genes. To determine the association of skeletal muscle PPARδ content with blood lipids and lipoproteins before and following exercise, overweight and obese men (n = 9) and women (n = 7) were recru...

Journal: :Indian journal of experimental biology 2000
B Andallu B Radhika

Hypoglycemic, diuretic and hypocholesterolemic effects of roots of W. somnifera (ashvagandha) were assessed on human subjects. Six mild NIDDM subjects and six mild hypercholesterolemic subjects were treated with the powder of roots of W. somnifera for 30 days. Suitable parameters were studied in the blood and urine samples of the subjects along with dietary pattern before and at the end of trea...

2013
Kandaswamy Selvakumar Senthamilselvan Bavithra Sekaran Suganya Firdous Ahmad Bhat Gunasekaran Krishnamoorthy Jagadeesan Arunakaran

Polychlorinated biphenyls exposure damages the rat liver cells. Hematological parameters such as hemoglobin, packed cell volume, red-blood cells, white-blood cells, neutrophils, platelet counts, and RBC indices were significantly decreased. Polymorphs, eosinophil counts, and erythrocyte sedimentation rate were significantly increased. Serum liver enzymes such as aspartate transaminase, alanine ...

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