As an ancient Chinese healing modality which has gained increasing popularity in modern society, acupuncture involves stimulation with fine needles inserted into acupoints. Both traditional literature and clinical data indicated that modulation effects largely depend on specific designated acupoints. However, scientific representations of acupoint specificity remain controversial. In the presen...

We consider the problem of transforming a set of elements into another by a sequence of elementary edit operations, namely substitutions, removals and insertions of elements. Each possible edit operation is penalized by a non-negative cost and the cost of a transformation is measured by summing the costs of its operations. A solution to this problem consists in defining a transformation having ...

Small cell lung cancer (SCLC) cells express and secrete bombesin-like peptides (BLP) that can activate specific receptors that stimulate the growth of these cells. A murine monoclonal antibody, 2A11, which binds to the BLP, gastrin-releasing peptide with high affinity, has been reported to decrease the growth of SCLC cells in vitro and in athymic nude mice. A Phase I trial in lung cancer patien...

INTRODUCTION Interleukin-32 (IL-32) is a recently described cytokine that is a strong inducer of pro-inflammatory cytokines such as tumor necrosis factor (TNF)-α, IL-1β, IL-6, and IL-8. The expression of this cytokine is highly increased in the rheumatoid synovium and correlated with the severity of joint inflammation. Little is known regarding the innate immune-related regulation of IL-32 by f...

The stationary field experiment on the application of different types and doses liming was started in Kupres plateu (1.184 m.a.s.l.), Bosnia Herzegovina summer 2017. aim this three-year research to determine effectiveness materials changes soil chemical properties yield cultivated crops. used treatments were; control, crude dolomite from Rama, Kupres, commercial burnt lime; each applied at lowe...

Purpose Although resting-state fMRI signal correlation has been widely used to infer functional connectivity and network organization of the brain, its neural correlate remains unclear. By analyzing correlation of band-limited power (BLP), several electrophysiological studies have suggested that the fMRI correlations may have contributions from neuronal oscillations at specific frequency bands....

Received: 16 November 2014 Abstract Accepted: 11 January 2015 In this paper, an Assembly Line Balancing Problem (ALBP) is presented in a real-world automotive cables manufacturer company. This company found it necessary to balance its line, since it needs to increase the production rate. In this ALBP, the number of stations is known and the objective is to minimize cycle time where both precede...

We extend the Berry, Levinsohn and Pakes (BLP, 1995) random coefficients discretechoice demand model, which underlies much recent empirical work in IO. We add interactive fixed effects in the form of a factor structure on the unobserved product characteristics. The interactive fixed effects can be arbitrarily correlated with the observed product characteristics (including price), which accommod...

We prove global rigidity for compact hyperbolic and spherical cone-3-manifolds with cone-angles ≤ π (which are not Seifert fibered in the spherical case), furthermore for a class of hyperbolic cone-3-manifolds of finite volume with cone-angles ≤ π, possibly with boundary consisting of totally geodesic hyperbolic turnovers. To that end we first generalize the local rigidity result contained in [...