A new chiral serine equivalent and its enantiomer have been synthesized from (S)- and (R)-N-Boc-serine methyl esters (Boc: tert-butyloxycarbonyl). The use of these compounds as chiral building blocks has been demonstrated in the synthesis of alpha-alkyl alpha-amino acids by diastereoselective potassium enolate alkylation reactions and subsequent acid hydrolyses. Theoretical studies were perform...

Silicon wafers and glass surfaces were functionalized with facially amphiphilic antimicrobial copolymers using the "grafting from" technique. Surface-initiated atom transfer radical polymerization (ATRP) was used to grow poly(butylmethacrylate)-co-poly(Boc-aminoethyl methacrylate) from the surfaces. Upon Boc-deprotection, these surfaces became highly antimicrobial and killed S. aureus and E. co...

Japan has been developing a new satellite based positioning system called Quasi-Zenith Satellite System (QZSS). Since improvement of positioning availability in urban area is one of the most important advantages of the QZSS, multipath mitigation is a key factor for the QZSS positioning system. Therefore, Japan Aerospace Exploration Agency (JAXA) and GNSS Inc. developed a pseudolite, which trans...

Recently, the authors have proposed a new class of BinaryOffset-Carrier (BOC) modulation, namely the Double-BOC (DBOC) modulation which generalizes the main modulation types used in GPS and Galileo under a single, unified formula, and allows extra-flexibility in designing the suitable spectral shaping of future GNSS signals. The goal of this paper is to extend the previous analysis to multipath...

The X-ray structure of the title compound was determined for first time. There are four independent molecules that form a repeat unit packed in crystal alternating pairs with orthogonal orientation and further joined into infinite chains by hydrogen bonding.

The reactions of N1,N2-Di-boc-1,2,4-triaminobutane with bridged dicarboxylic acids afford the corresponding bis-amides from which – after removal of the Boc groups – bis(N,N′-bidendate) ligands H2NCH2CH(NH2)(CH2)2NHCO-X-CONH(CH2)2CH(NH2)CH2NH2 can be obtained. New examples are the reactions of the triaminobutane with pyridine-2,6-dicarboxylic acid, with phenylene-1,4-diacetic acid, with terepht...

This paper addresses a novel cosine-phased binary offset carrier (BOC) signal tracking, enabling an unambiguous signal tracking. Two novel locally-generated signals are first obtained by dividing the cosine-phased BOC sub-carrier into multiple parts, and then, cross-correlations between each of the locally-generated signals and the received signal are generated. Finally, the cross-correlations ...

Although enantioconvergent alkyl-alkyl couplings of racemic electrophiles have been developed, there have been no reports of the corresponding reactions of racemic nucleophiles. Herein we describe Negishi cross-couplings of racemic α-zincated N-Boc-pyrrolidine with unactivated secondary halides, thus providing a one-pot, catalytic asymmetric method for the synthesis of a range of 2-alkylpyrroli...

We have previously developed water-based microwave (MW)-assisted peptide synthesis using Fmoc-amino acid nanopaticles. It is an organic solvent-free, environmentally friendly method for peptide synthesis. Here we describe water-based MW-assisted solid-phase synthesis using Boc-amino acid nanoparticles. The microwave irradiation allowed rapid solid-phase reaction of nanoparticle reactants on the...

The decapeptides Boc-(Aib-L-Ala)s-OMe and Boc-(Aib-L-Val)s-OMe have been studied by 270-MHz lH-nmr in CDCl3 and (CD&SO solutions. Intramolecular hydrogen-bonded NH groups have been delineated using the temperature and solvent dependence of the NH chemical shifts and differential broadening of the NH resonances, induced by addition of a nitroxide radical. Both peptides have eight solvent-shielde...