Coronavirus disease 2019 (COVID-19) has become a new pandemic with over 190000 cases and 7800 death reported world-wide as of 18 March 2020. Due to its high infectivity pathogenicity, most people are vulnerable this virus, especially those comorbidities. According previous study, patients pre-existing conditions more likely require mechanical ventilation, which may lead higher risk death. Post-...

THE goal of tolerance induction, although achievable in pre-clinical models, is not yet a clinical reality. One of the most important areas of experimental research in thc field of tolerance induction has been the administration of donor-specific bone marrow in conjunction with whole organ transplantation. The same strategy has been tested in several clinical trials; all have included chronic i...

Machado et al1 should be congratulated on seizing the opportunity of the 1997 measles outbreak in São Paulo, Brazil, for learning about measles in marrow transplant recipients. Per the report, only 8 of 156 patients (5.1%) developed measles, and only 1 patient (0.6%) had a severe disease (measles pneumonia). But both the incidence and the severity of measles were likely underestimated. Measles ...

TT virus (TTV) is a newly discovered transfusion-transmissible DNA virus, which may cause posttransfusion hepatitis. The virus was detected in 12% of Japanese blood donors. The aim of the study is to investigate the prevalence and clinical influence of TTV in bone marrow transplant (BMT) recipients. Sera from 25 BMT recipients obtained 6 to 12 weeks after the transplant were examined for TTV-DN...

OBJECTIVE To identify the psychiatric illnesses in patients with hematological/oncological disorders encountered during blood and bone marrow transplantation. DESIGN Cross-sectional study. PLACE AND DURATION OF STUDY Bismillah Taqee Institute of Health Sciences and Blood Diseases Centre, Karachi from December 2002 to December 2005. PATIENTS AND METHODS All consecutive patients, aged 15 ye...

introduction: the majority of leukemia patients are acute leukemia patients, so that about 70.8% lymphoblastic leukemia were acute lymphoblastic leukemia (all) patients and 66.4 % of myeloid leukemia patients were acute myeloid leukemia (aml) in tehran metropolitan. during the last two decades, intensification of therapy by the use of high-dose cytarabine allogeneic stem cell transplantation in...

Human cytomegalovirus (CMV) infection is common in most people but nearly asymptomatic in immunocompetent individuals. After primary infection the virus persists throughout life in a latent form in a variety of tissues, particularly in precursor cells of the monocytic lineage. CMV reinfection and occurrence of disease are associated with immunosuppressive conditions. Solid organ and bone marrow...

Philadelphia chromosome (Ph1)-positive acute lymphoblastic leukemia (ALL) has a poor prognosis when treated with conventional chemotherapy. We analyzed the outcome of 67 HLA-identical sibling bone marrow transplants (BMTs) for Ph1-positive ALL reported to the International Bone Marrow Transplant Registry (IBMTR). Twenty-one of 67 (31%) transplant recipients survived in continuous complete remis...