Sclerostin (SOST) is an extracellular Wnt signaling antagonist which negatively regulates bone mass. Despite this, the expression and function of SOST in skeletal tumors remain poorly described. Here, we first describe the immunohistochemical staining pattern of SOST across benign and malignant skeletal tumors with bone or cartilage matrix (n=68 primary tumors). Next, relative SOST expression w...

Objective: The objective of this study was to present a review article about temporal bone vascular tumors. Data Sources: Published English-language literatures in PubMed and Google scholar. Review methods: PubMed and Google scholar were systematically searched using search terms: angisarcoma, temporal and bone, hemangioendothelioma, temporal and bone. Kaposi, sarcoma, temporal and bone, hemang...

Diagnostic imaging plays a pivotal role in the initial detection, characterization, pre-operative assessment and long term follow-up of malignant bone tumors. The purpose of this brief review is to discuss the specific role of the different imaging modalities in the diagnostic work-up of malignant bone tumors. The imaging features, with emphasis on standard radiography, allowing differentiation...

Few examples of osteomas the facial bones have been documented in literature making them a rare condition. When found craniofacial skeleton, are benign, slow-growing osteogenic tumors bone that distinguished by growth compact or cancellous bone. The case report this article describes peripheral osteoma near angle mandible which was diagnosed incidentally cone beam computed tomography scan. We s...

Introduction: Osteomas are asymptomatic and rare slow growing bony tumors in temporal bone, and should be taken into account in differential diagnosis of the osteolytic solitary skull lesions. Sometimes is associated with pain and functional loss. Only a few cases have been reported.   Case Report: We describe a case of an osteoid osteoma of the temporal bone (mastoid) in a 31-year-old woman pr...

OBJECTIVE We aimed to understand the biology of osteosarcoma of the flat bone, which is a rare tumor entity. METHODS Cases with osteosarcoma of the flat bone were compared with those of the extremity in order to evaluate their clinicopathologic characteristics. And the influences of heterogeneous treatment modalities on outcome were analyzed. RESULTS Tumors of the flat bone comprised 91 (11...

SPONTANEOUS BONE tumors in mice are rare. Pybus and Miller (1, 2) described a subline of Simpson mice which had a high incidence of bone tumors, but descendants of these mice no longer develop bone tumors. Apart from this series, most reports have been of single tumors usually in C3H mice (3) or their hybrids (4). Dunn (personal communication) observed an osteogenic sarcoma with metastases in a...

Parosteal bone tumors involving the small bones of the hand and the foot are rare. Their clinical and imaging features may imitate other bone tumors, leading to incorrect diagnosis and management. Histological examination of the lesion will establish the correct diagnosis. Bizarre parosteal osteochondromatous proliferation was first described in 1983 by Nora et al.1 In a report of 35 Mayo Clini...

introduction: osteomas are asymptomatic and rare slow growing bony tumors in temporal bone, and should be taken into account in differential diagnosis of the osteolytic solitary skull lesions. sometimes is associated with pain and functional loss. only a few cases have been reported.   case report: we describe a case of an osteoid osteoma of the temporal bone (mastoid) in a 31-year-old woman pr...