Abstract Background ESBLs hydrolyze the beta-lactam ring of antibiotics and are not affected by 1st, 2nd, 3rd, 4th generation antibiotics. There over 400 ESBL enzymes that have already been investigated globally present in Enterobacteriaceae species such as Escherichia coli , Klebsiella pneumoniae oxytoca strains. Prevalence is slowly increased, from 10 to 40% E. K. pneumonia Microorganisms pro...