Sex differences in the incidence of varicose veins have been suggested; however, the venous mechanisms involved are unclear. We hypothesized sex-related differences in venous function and underlying distinctions in intracellular free calcium, [Ca(2+)](i), signaling and Ca(2+)-dependent mechanisms of venous contraction. Circular segments of inferior vena cava (IVC) from male and female Sprague-D...

a School of Medicine, Genetic Diagnostic Laboratory Haig KaLaboratory Faye A. Eggerding, M.D., Director Georgetown University Medical Center, Molecular Diagnostic Laboratory Lee-Jun C. Wong, Ph.D., Director Mayo Clinic, Molecular Genetics Laboratory Stephen N. Thibodeau, Ph.D., Director Memorial Sloan-Kettering Cancer Center, Diagnostic Molecular Genetics Nathan A. Ellis, Ph.D., Director Myriad...

Pavlakis, N., Sjoquist, K., Martin, A., Tsobanis, E., Yip, S., Kang, Y., Bang, Y., Alcindor, T., O'Callaghan, C., Burnell, M., Wong, K., Simes, R., et al (2016). Regorafenib for the treatment of advanced gastric cancer (INTEGRATE): A multinational placebo-controlled phase II Trial. Journal of Clinical Oncology, 34(23), 2728-2735. [More Inform...

Please cite this article as: Kerstin Pannek, Jurgen Fripp, Joanne M. George, Simona Fiori, Paul B. Colditz, Roslyn N. Boyd, Stephen E. Rose , Fixel-based analysis reveals alterations is brain microstructure and macrostructure of preterm-born infants at term equivalent age. The address for the corresponding author was captured as affiliation for all authors. Please check if appropriate. Ynicl(20...

Mark Lawler, PhD; Anna Gavin, MD; Manuel Salto-Tellez, MD; Richard D. Kennedy, MD, PhD; Sandra Van Schaeybroeck, MD, PhD; Richard H. Wilson, MD; Denis Paul Harkin, PhD; Margaret Grayson; Ruth E. Boyd; Peter W. Hamilton, PhD; Darragh G. McArt, PhD; Jacqueline James, PhD; Tracy Robson, PhD; Robert D. Ladner, PhD; Kevin M. Prise, PhD; Joe M. O’Sullivan, MD; Timothy Harrison, PhD; Liam Murray, MD; ...

TO THE EDITOR—We welcome with great interest a randomized controlled trial to evaluate the efficacy of doxycycline prophylaxis for sexually transmitted infections (STIs) as proposed by Boyd et al [1, 2], although we offer several concerns: Syphilis is readily treatable and curable; doxycycline prophylaxis, therefore, would be considered an alternative to guideline-recommended quarterly testing ...

D. Naples, T. Adams, A. Alton, S. Avvakumov, L. de Barbaro, P. de Barbaro, R. H. Bernstein, A. Bodek, T. Bolton, S. Boyd, J. Brau, D. Buchholz, H. Budd, L. Bugel, J. Conrad, R. B. Drucker, B. T. Fleming, J. Formaggio, R. Frey, J. Goldman, M. Goncharov, D. A. Harris, J. H. Kim, S. Koutsoliotas, R. A. Johnson, M. Lamm, W. Marsh, D. Mason, K. S. McFarland, C. McNulty, P. Nienaber, V. Radescu, A. R...