BACKGROUND AND PURPOSE Autonomic failure is known to manifest commonly in stroke, but very little attention has been given to various features of sympathetic dysfunction such as sudomotor dysregulation in cerebrovascular diseases. In the present study, our purpose was to assess quantitatively sympathetic reflex activity in brain infarction by measuring the sympathetic skin response. METHODS W...

The global pandemic of coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome 2 (SARS-CoV-2) persists despite the progress vaccination and increased natural immunity. SARS-CoV-2 associated not only with pneumonia distress, but also many symptoms related to central nervous system (CNS), including loss sense taste smell, headache, convulsions, visual disturbances, impa...

Introduction: Arterial hypertension is one of the causes of stroke, and as one of the vasculotoxic conditions intensifies ischemic stroke complications. The aim of the present study was to analyze the effects of short-term cerebral hypertension on ischemia/reperfusion injury and pathogenesis of ischemic stroke. Methods: The experiments were performed on three groups of rats (N=36) Sham, cont...

Background & Aims: Stroke is the third leading cause of death. Oxidative stress has a principal role in the complications of stroke. Due to this fact and the antioxidant effects of ascorbic acid, this study was designed to evaluate the effect of ascorbic acid on reduction of stroke complications in a permanent model of middle cerebral artery (MCA) occlusion in male rats. Methods: In this experi...

Primary vasculitis of the central nervous system (PACNS) is a rare form unknown cause that affects vessels brain, spinal cord and meninges without systemic damage. It was found average age onset disease 50 years. Clinical manifestations depend on caliber affected vessels. The most common initial symptoms are headache vascular cognitive impairment associated with small vessel involvement. develo...