introduction: breast neoplasia is the most common cancer among women in both developed and developing countries. over 1.15 million women in the world detecting with breast neoplasia each year and the mortality rate is 502,000 cases from this cancer. the purpose of this study was to describe how iranian women perform breast self-examination. materials and methods: in this cross-sectional study 4...

Abstract BACKGROUND: Craniectomies requiring skull reconstruction are indicated following oncological resection of masses involving the underlying brain and/or skull. Immediate cranioplasties have previously been performed using suboptimal hand-bending or molding techniques ‘‘off – shelf’’ products. Today with computer aided design, customized craniofacial implants become widely available for p...

Hypoxia is known to be an important prognostic marker in many human cancers. We report the use of two oxygen measurement techniques in human brain tumors and compare these data with semiquantitative histological end points. Oxygenation was measured using the Eppendorf needle electrode and/or EF5 binding in 28 brain tumors. These data were compared with necrosis, mitosis, and endothelial prolife...

Beclin 1 is is an autophagy gene, the role of which as a tumour suppressor has recently been recognized in a few studies. We examined the expression of Beclin 1 protein in 212 primary human brain tumours, including 97 high-grade glial tumours, 29 low-grade glial tumours, 4 grade III meningiomas, 19 grade II meningiomas, 52 grade I meningiomas, and 11 medulloblastomas. In 94 cases, including 56 ...

OBJECTIVES To update and assess mortality from neoplasms to 31 December 1995 among 10 109 men employed in a job exposed to vinyl chloride for at least 1 year between 1942 and 1972 at any of 37 North American factories. Previous analyses indicated associations between employment in vinyl production and increased mortality risk from cancers of the liver and biliary tract, due to increased mortali...

the aim of this study was to determine the prognosis and survival for patients with borderlineovarian tumor (bot). a retrospective review of 30 patients with serous andmucinous bot treated at or referred to our institution was performed. fifteenpatients (50%) had serous, and the others had mucinous bot. about 86% of allpatients in both groups were in stage i of the disease. the recurrent diseas...

Metallothioneins take part in the homeostasis of the ions of the metals which are necessary for the proper metabolism of the organism (zinc, copper), in biosynthesis regulation of the zinc-containing proteins and also in the detoxication of metals from the tissues. They also protect the tissue from the effects of free radicals, radiation, electrophilic pharmacological agents used in the cancer ...