Whereas numerous studies document the effects of dopamine medication and deep brain stimulation on motor function in patients with Parkinson's disease, few have investigated deep brain stimulation-induced changes in sensory functions. In this study of 13 patients with Parkinson's disease, we tested the effects of deep brain stimulation on the somatosensory temporal discrimination threshold. To ...

Deep Brain Stimulation Chikashi FUKAYA, Kazutaka KOBAYASHI, Hideki OSHIMA, Takamitsu YAMAMOTO and Yoichi KATAYAMA Neuromodulation Center, Nihon University Hospital Department of Neurological Surgery and Division of Applied System Neuroscience, Nihon University School of Medicine Deep brain stimulation (DBS) is an important component of the therapy for movement disorders and intractable pain. In...

Long-term results show that benefits from chronic deep brain stimulation in dystonia are maintained for many years. Despite this, the neurophysiological long-term consequences of treatment and their relationship to clinical effects are not well understood. Previous studies have shown that transcranial magnetic stimulation measures of abnormal long-term potentiation-like plasticity (paired assoc...

Abstract Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective surgical treatment for Parkinson’s disease (PD), alleviating motor symptoms and restoring patients’ quality life. Research into long-term effects DBS on human lacking. This study aims to investigate neuroanatomical neurochemical alterations induced by chronic stimulations STN, correlate these changes with cli...

Person authentication using biometric information has recently become popular among researchers. User management based on biometrics is more reliable than that conventional methods. To secure private information, it necessary to build continuous authentication-based user systems. Brain waves are suitable modalities for authentication. This study brain evoked by invisible visual stimuli. Invisib...

Non-invasive transcutaneous vagus nerve stimulation elicits similar therapeutic effects as invasive stimulation, offering a potential treatment alternative for wide range of diseases, including epilepsy. Here, we present novel, non-invasive the nerve, which is performed manually viscero-osteopathically on abdomen (voVNS). We explore impact short-term voVNS various local and global characteristi...