background: idiopathic granulomatous mastitis (igm) is a rare benign breast disease, which can mimic breast cancer. as the managements of igm and breast cancer are entirely different and the initial clinical manifestations are similar in several cases, it is very important to differentiate them. case presentation: we reported a 48-year-old female patient with igm and breast cancer. she was refe...

background: potential association of leptin (lep) gene polymorphisms has been suggested in the processes leading to breast cancer initiation and progression. we investigated whether genetic variations in the lep -2548g/a gene are associated with risk of breast cancer. methods: this case-control study consisted of 100 breast cancer cases and 100 control subjects without breast cancer that matche...

mri of the breast has evolved as a non-invasive imaging modality and is ideally suited for several indications e.g. pre-operative staging and screening in women at increased risk for breast cancer. the widespread use opens also the discussion on over-diagnosis if only 20 - 30 out of 100 mri - guided breast biopsies lead to the diagnosis of breast cancer. thus mri based strategies are needed to ...

Background: Breast cancer incidence has increased rapidly inKuwait, but there haven’t been any studies investigating the recognized risk factors of breast cancer inKuwait. The aim of the study was to investigate breast cancer risk factors among women inKuwait. Methods: A case-control study was conducted in Kuwait from May 2003 to March 2004 using a questionnaire including socio-demographic data...

Background: Prediction of breast cancer risk and identifying women who are at high risk of breast cancer, would be a great help for planning and conducting screening programs. The aim of this study was to estimate the 5-year breast cancer risk among women in Isfahan. Methods: This cross-sectional study was conducted on 9674 women aged 35-69 years who referred to the Breast Cancer Screening Cen...

abstract background: the increase in breast cancer incidence has enhanced attention towards breast cancer risk. the aim of this study was to determine the risk of breast cancer and risk perception of women, factors that affect risk perception, and to determine differences between absolute risk and the perception of risk. methods: this cross-sectional study was carried out among 346 women whose ...

background: cancer/testis antigens (ctas) are members of a group of proteins which are normally expressed in testis germ cells and to a lesser extent in the ovaries. because of recent reports about their aberrant and specific expression in some tumoral tissues, they may play a role as new candidates for targeted therapy. therefore, the study of the expression pattern of these biomarkers and its...

BACKGROUND AND PURPOSE The purpose of this study is to analyze the patterns of local recurrence (LR) after intra-operative radiotherapy (IORT) containing multimodality treatment of locally advanced rectal carcinoma (LARC). METHODS AND MATERIALS Two hundred and ninety patients with LARC who underwent multimodality treatment between 1994 and 2006 were studied. For patients who developed LR, the...

Ten brain tumor patients underwent wide resection of the tumor followed by Intraoperative Radiation Therapy (IORT) at the first surgery or at the second salvage surgery after failure of conventional external beam irradiation. Two patients(1 meningioma, 1 glioblastoma multiforme) were treated at the first surgery and 8 patients(3 anaplastic astrocytoma, 3 glioblastoma multiforme, 1 meningioma, 1...