This paper applies artificial neural networks (ANNs) to the survival analysis problem. Because ANNs can easily consider variable interactions and create a non-linear prediction model, they offer more flexible prediction of survival time than traditional methods. This study compares ANN results on two different breast cancer datasets, both of which use nuclear morphometric features. The results ...

CONTEXT Soy foods are rich in isoflavones, a major group of phytoestrogens that have been hypothesized to reduce the risk of breast cancer. However, the estrogen-like effect of isoflavones and the potential interaction between isoflavones and tamoxifen have led to concern about soy food consumption among breast cancer patients. OBJECTIVE To evaluate the association of soy food intake after di...

Purpose An association between endocrine treatment-related symptoms and breast cancer recurrence has been suggested previously; however, conflicting results have been reported. We performed a meta-analysis of published studies to clarify this relationship. Methods We systematically searched PubMed, Embase, Scopus, and the Cochrane database for studies investigating the association between end...

Background: Breast phyllodes tumor (PT), the rare fibroepithelial mammary is composed by mesenchymal and epithelial components, only 1%~2% of which were accompanied breast cancer. The incidence non-invasive ductal carcinoma (DCIS) arising in benign PTs even rarer. There no certain treatment for it currently because low PT with DCIS. Case Description: Here, we report a 57-year-old female patient...

To date, there have been no tumor biomarkers validated and incorporated into oncologic practice for the early diagnosis of breast cancer. Recently, we showed that sperm-associated antigen 9 (SPAG9), a member of cancer testis (CT) antigen family, is associated with ovarian carcinomas. In the present study, we investigated SPAG9 expression and humoral immune response in breast cancer. We further ...

OBJECTIVE: To evaluate ipsilateral breast tumor recurrence after breast-conserving surgery for locally advanced breast cancer. METHODS: A retrospective observational cohort study was performed in patients with locally advanced breast cancer submitted to breast-conserving surgery after neoadjuvant chemotherapy based on an adriamycin-cyclophosphamide-paclitaxel regimen. We evaluated the clinica...

Several studies have indicated that magnetic resonance imaging radiomics can predict survival in patients with breast cancer, but the potential biological underpinning remains indistinct. This study aims to develop an interpretable deep-learning-based network for classifying recurrence risk and revealing underpinning. In this multicenter study, 1,113 nonmetastatic invasive cancer were included,...

Objective: This study aimed to analyse the risk factors of the recurrence and metastasis of breast cancer after breast-conserving surgery. Methods: There were 102 breast cancer patients who underwent breast surgery reservations in 404 Hospital of the Chinese People’s Liberation Army from January 2011 to December 2014. We had recorded these cases’ 5-y recurrence rate and transfer rate after 1-5 ...