Diffusion weighted MRI has become ubiquitous in many areas of medicine, including cancer diagnosis and treatment response monitoring. Reproducibility of diffusion metrics is essential for their acceptance as quantitative biomarkers in these areas. We examined the variability in the apparent diffusion coefficient (ADC) obtained from both postprocessing software implementations utilized by the NC...

In our study, we aimed to measure the dose exposed by fetus during three-dimensional conformal radiotherapy (3D-CRT) and intensity-modulated (IMRT) treatment techniques in pregnant patients who had undergo due breast cancer with thermoluminescence dosimetry (TLD) compare these measurements planning system (TPS). 2.5 mm- thick computed tomography (CT) images of Alderson Rando phantom device were...

background: this study assessed the clinical usefulness of the solid phantom, which may compensate for the disadvantages of the water phantom, by comparing the radiological doses between the two depending on their depths. materials and methods: the experimental equipment used was a linear accelerator for medical use, water phantom, solid phantom, farmer type ion chamber and electrometer. the di...

We designed, fabricated and tested a novel imaging system that fuses diffuse optical tomography (DOT) and photoacoustic tomography (PAT) in a single platform. This platform takes advantages of both DOT and PAT, and can potentially provide dual-modality two dimensional functional and cellular images of the breast quantitatively. Here we describe this integrated platform along with initial tissue...

SPECT detects γ-rays from administered radiopharmaceutical within the patient body. γ-rays pass through different tissues before reaching detectors and are attenuated. Attenuation can cause artifacts; therefore different methods are used to minimize attenuation effects. In our study efficacy of Chang method was evaluated for attenuation purpose, using a custom made heart phantom. Due to d...

The quality and realism of simulated images is currently limited by the quality of the digital phantoms used for the simulations. The transition from simple raster based phantoms to more detailed geometric (mesh) based phantoms has the potential to increase the usefulness of the simulated data. A preliminary breast phantom which contains 12 distinct tissue classes along with the tissue properti...

With the rapid development of China's space industry, the importance of radiation protection is increasingly prominent. To provide relevant dose data, we first developed the Visible Chinese Human adult Female (VCH-F) phantom, and performed further modifications to generate the VCH-F Astronaut (VCH-FA) phantom, incorporating statistical body characteristics data from the first batch of Chinese f...

BACKGROUND The OneDosePlusTM system, based on MOSFET solid-state radiation detectors and a handheld dosimetry reader, has been used to evaluate intra-fraction movements of patients with breast and prostate cancer. METHODS An Action Threshold (AT), defined as the maximum acceptable discrepancy between measured dose and dose calculated with the Treatment Planning System (TPS) (for each field) h...

Conventional radar-based image reconstruction techniques fail when they are applied to heterogeneous breast tissue, since the underlying in-breast relative permittivity is unknown or assumed to be constant. This results in a systematic error during the process of image formation. A recent trend in microwave biomedical imaging is to extract the relative permittivity from the object under test to...

We are developing a method using nonrigid co-registration of PET and MR breast images as a way to improve diagnostic specificity in difficult-to-interpret mammograms, and ultimately to avoid biopsy. A deformable breast model based on a finite-element method (FEM) has been employed. The FEM “loads” are taken as the observed intermodality displacements of several fiducial skin markers placed on t...