background : st6gal1, cox-2 and hb-egf genes are involved in different tumors and their enhanced expressions often correlate with poor prognosis. in this study we assay the expressions of these genes by reverse transcriptase-pcr in 54 breast cancer samples. methods : tissue samples were either formalin-fixed for histopathological examination or frozen for reverse transcriptase-pcr. image progra...

OBJECTIVES To determine the sensitivity of breast-specific gamma imaging (BSGI) in diagnosing breast cancer and assess the potential correlation between the semiquantitative index of BSGI and biologic markers, molecular subtypes, and clinicopathologic characteristics of breast cancer. MATERIALS AND METHODS The sensitivity of BSGI for breast cancer was retrospectively assessed in 102 female br...

Introduction and aim. Large breast sizes frequently contribute to women presenting with severe pain symptoms. This study determined the association between hypertrophy, forward head posture (FHP), neck shoulder related disabilities selected anthropometric variables of female undergraduate students College Medicine, University Lagos. Material methods. A cross-sectional analytical was conducted a...

Introduction The first medical intervention for many breast cancer patients is breast conserving surgery (BCS) and/or modified radical mastectomy (MRM). Most of these patients undergo radiation therapy, following surgery. The most common side-effect of breast radiotherapy is skin damage. In the present study, the severity of acute skin changes and the underlying causes were investigated in pati...

PURPOSE Insulin-like growth factors (IGFs) are potent mitogens for breast cancer cells in vitro, and elevated IGF-I serum levels are a risk factor for breast malignancies. This study evaluated IGF-I and IGF-II serum levels in healthy women and in patients with benign and malignant breast lesions and correlated them with tumor size. EXPERIMENTAL DESIGN Serum levels of the total and unbound fra...

BACKGROUND Little information is available on the use of chest computed tomography (CT) to predict breast tumor size in breast cancer, despite the fact that chest CT examinations are being increasingly used. The purpose of this study was to evaluate the value of chest CT for predicting breast tumor size using pathology measurements as reference standards. METHODS Tumor sizes (defined as great...

PURPOSE Noninvasive image-guided breast brachytherapy delivers conformal HDR (192)Ir brachytherapy treatments with the breast compressed, and treated in the cranial-caudal and medial-lateral directions. This technique subjects breast tissue to extreme deformations not observed for other disease sites. Given that, commercially-available software for deformable image registration cannot accuratel...

BACKGROUND Breast conservative surgery (BCS) followed by radiotherapy is the standard approach in management of stage I-II breast cancer. Several factors can affect cosmetic outcomes. The aim of this study was to evaluate the cosmetic results of BCS and influencing factors in the Iranian Breast Cancer Research Center. MATERIALS AND METHODS Patients who had undergone BCS were included. Photogr...

BACKGROUND The preoperative prediction of therapeutic breast reduction weights, to achieve both relief of breast weight symptoms and yet achieve excellent breast shape, remains a challenge. OBJECTIVES To design a simple clinical method to preoperatively predict and quantify therapeutic breast reduction weights. METHODS In 31 women who underwent therapeutic bilateral reduction mammaplasty, t...