Nonfunctional ribosomal RNA decay (NRD) is a novel quality control system that eliminates defective ribosomal RNAs (rRNAs) from yeast cells. Plasmid-encoded rRNAs containing single nucleotide substitutions in the peptidyl transferase center of 25S rRNA or the decoding center of 18S rRNA are co-expressed with endogenous rRNAs in Saccharomyces cerevisiae. Quantitative northern blots reveal the st...

This paper conducts a detailed review of the seismic hazard, inventory, bridge vulnerability, and bridge retrofit practices in the Central and Southeastern United States CSUS . Based on the analysis of the bridge inventory in the CSUS, it was found that over 12,927 bridges 12.6% are exposed to 7% probability of exceedance PE in 75-year peak ground acceleration PGA of greater than 0.20 g, and ne...

The crystal structure of the thermostable indoleglycerol-phosphate synthase from Thermotoga maritima (tIGPS) was determined at 2.5 A resolution. It was compared with the structures of the thermostable sIGPS from Sulfolobus solfataricus and of the thermolabile eIGPS from Escherichia coli. The main chains of the three (beta alpha)(8)-barrel proteins superimpose closely, and the packing of side ch...

The present bridge network in Quebec includes approximately 9000 bridges of different types and represents a 9 billion dollars asset. Many bridges show signs of deterioration well before the end of the design life, supposedly between 50 to 100 years. Truck loading has increased by more than 40% in the past 40 years, and bridges have not been reinforced in order to comply with the new codes. The...

Let K be a subgraph of G. It is shown that if G is 3–connected moduloK then it is possible to replace branches ofK by other branches joining same pairs of main vertices of K such that G has no local bridges with respect to the new subgraph K. A linear time algorithm is presented that either performs such a task, or finds a Kuratowski subgraph K5 or K3,3 in a subgraph of G formed by a branch e a...

∗Research supported by NSERC and FQRNT. †Département d'Informatique et de Génie Logiciel, Université Laval, Québec, Canada. [email protected] ‡School of Computer Science, McGill University, Montréal, Canada. [email protected] The algebraic theory of nite automata has been one of the most successful tools to study and classify regular languages. These very same tools can in fact be us...

Intelligent Systems Division, National Institute of Standards and Technology, Gaithersburg, Md. 20899. The National Institute of Standards and Technology (NIST) has developed conceptual designs, laboratory scale models, and computer simulations/animation of several configurations of remotely operated cranes to assemble highway bridges. NIST’s designs have been patented and trademarked as “RoboC...

Population growth followed by the dramatic increase and demand for new services created an urgent and overwhelming need for infrastructures of civil engineering structures. However, the current infrastructure work using various techniques and conventional materials for construction will not solve the traditional and continuous deterioration of concrete structures due to corrosion of steel. One ...

Left ventricular assist devices (LVADs) have revolutionized the care of heart failure. They now provide another therapeutic option for many patients, transplant eligible or ineligible, with symptoms refractory to medical therapy and resynchronization therapy. For appropriately selected patients, LVADs offer improvements in both quality and length of life. The enthusiasm for LVAD use in the card...

we develop a simplified version of a variational principle within Nelson stochas-tic mechanics that produces the von Neumann wave packet reduction after a position measurement. This stochastic control problem parallels, with a different kinematics, the problem of the Schrödinger bridge. This gives a profound meaning to what was observed by Schrödinger in 1931 concerning Schrödinger bridges: " M...